The H protein displays a single-chain antibody (scFv) specific for the target receptor and is ablated for recognition of the MV receptors CD46 and SLAM by point mutations in its …

CD46 is the receptor of fiber 35 proteins, allowing U251 cells to bind to KGHV500 and KGHV400. We found that U251 cells overexpressed p21H-Ras, which led them to be the target of anti …

Feb 3, 2021 · By fusing a high-affinity CD46 specific single-chain antibody fragment (scFv) to the CDV-Hemagglutinin (H), ablating its tropism for human nectin-4 and modifying the CDV …

Nov 12, 2018 · We explored whether CIK cells could carry the recombinant adenovirus KGHV500 containing the anti-p21Ras single chain fragment variable antibody (scFv) gene into tumors …

Jun 26, 2013 · We demonstrate that transient scFv-Fc production in HEK293-6E is robust, versatile and highly efficient and can overcome the bottleneck of antibody production in a high …

Expression of the complement-regulatory proteins (CRP) CD46, CD55 and CD59 represents a strategy used by tumor cells to evade complement-dependent cell cytoxicity stimulated by …

A single-chain variable fragment (scFv) is not actually a fragment of an antibody, but instead is a fusion protein of the variable regions of the heavy (V H) and light chains (V L) of …

To enable highly speci fic targeting of CD90+ HSCs, we designed CD90-targeted viral vectors engineering an anti-CD90 single chain variable fragment (scFv) onto measles- and VSV-G …

In this study, we explored the potential of single chain variable fragments (scFv) as targeting domains to achieve delivery of exosomes to cells expressing a cognate antigen.

Oct 19, 2003 · We show that ectopic expression of human CD46 rendered nonhuman cells susceptible to infection with group B viruses in vitro and in vivo. In addition, both siRNA …