In the presence of oxidative stress, AMPK promotes cytoprotection by enhancing the conservation of energy by suppressing protein translation and by stimulating autophagy. AMPK interplays …

Here, we report that in primary mouse adipocytes, PKA associates with and phosphorylates AMPKα1 at Ser-173 to impede threonine (Thr-172) phosphorylation and thus activation of …

Adenosine monophosphate-activated protein kinase (AMPK) is a conserved, redox-activated master regulator of cell metabolism. In the presence of oxidative stress, AMPK promotes …

AMPK is a highly conserved sensor of intracellular adenosine nucleotide levels that is activated when even modest decreases in ATP production result in relative increases in AMP or ADP. In …

Oct 4, 2017 · AMP-activated protein kinase (AMPK) is a highly conserved sensor of low intracellular ATP levels that is rapidly activated after nearly all mitochondrial stresses, even …

Apr 1, 2021 · Luteinizing hormone (LH) via protein kinase A (PKA) triggers ovulation and formation of the corpus luteum, which arises from the differentiation of follicular granulosa and …

AMP-activated protein kinase (AMPK) is the primary sensor of cellular energy through adenine nucleotide levels that evolved and is maintained across all eukaryotic organisms. AMPK …

Mar 8, 2016 · We propose a mechanism by which AMPK activation antagonizes glucagon signalling by phosphorylating and activating the major hepatic cyclic nucleotide …

Nov 8, 2019 · To understand the mechanism by which PKA activates mTOR, we began by studying intracellular kinases known to modulate mTOR function. Although AMP-activated …

We detected AMPK phosphorylation (AMPKα (Ser173)) by PKA, which was increased in glucose starved cells and was associated with diminution of AMPK activation. To better explore this …