Antibodies that detect CD8 can be used in several scientific applications, including Flow Cytometry, Immunohistochemistry, Western Blot, Immunocytochemistry and ELISA. These antibodies target CD8 in Human, Mouse, Rat, Chicken and Avian samples.

CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck. Phosphate-buffered solution, pH …

Positron emission tomography imaging with 89 Zr-labeled anti-CD8 cys-diabody reveals CD8 + cell infiltration during oncolytic virus therapy in a glioma murine model.

CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation.

CD8α (D8A8Y) Rabbit mAb recognizes endogenous levels of total CD8α protein. Monkey species reactivity is Immunohistochemistry (Paraffin) only. Human, Monkey. Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human CD8α protein.

This anti-CD8 antibody was tested in order to establish a panel to describe and distinguish peripheral blood lymphocytes (from human PBMCs). Clone REA734 recognizes the human CD8 antigen, a cell-surface glycoprotein also known as Leu-2 or CD8a.

We offer antibodies to detect CD8 that have been cited in 40+ publications. Browse our catalog of monoclonal, polyclonal, and CD8-conjugated antibodies. Validated research applications for our CD8 antibodies include Blocking/Neutralizing, CyTOF-ready, Dual RNA-scope ISH-IHC, ELISA, Flow Cytometry, ICC, Immunofluorescence, IHC-Frozen, IHC ...

Feb 8, 2019 · We show here that two commonly used mAbs, against either the CD8α or CD8β subunit, can differentially affect cellular metabolism. Further, in vivo treatment leaves behind a population of CD8+ T cells with different phenotypic and functional attributes relative to each other or control CD8+ T cells.