PO Alternatives to Commonly Prescribed IV Antibiotics (Those that are NOT automatic switches per IV to PO Policy) The following alternatives are not automatic switches per the IV to PO policy due to either poor oral bioavailability or lacking in antimicrobial coverage compared to …

Timely conversion from intravenous (IV) to oral (PO) antimicrobial therapy is effective for a variety of infections, especially for agents with excellent bioavailability.

Recent studies support using oral antibiotics to treat many infections. If your patient is receiving IV antibiotics, consider a switch to oral if: Review reported susceptibilities. Possible oral options include:

Indicated for treatment of nosocomial pneumonia (moderate to severe) caused by beta-lactamase producing isolates of Staphylococcus aureus and by piperacillin/tazobactam-susceptible...

Aug 22, 2024 · What is Zosyn? Zosyn contains a combination of piperacillin and tazobactam. Piperacillin and tazobactam are penicillin antibiotics that fight bacteria in the body. Zosyn is used to treat many different infections caused by bacteria, such as stomach infections, skin infections, pneumonia, and severe uterine infections.

Aug 1, 2024 · Some IV to PO conversions are easy (linezolid, azithromycin), but some require more thought. If a provider wants some IV to PO suggestions, the following are some to consider.

IV to PO Antibiotic Step-Down Guidelines. Candidates for Antimicrobial Step -Down therapy: • Patient is able to tolerate PO medication . AND. has a functioning GI tract • The infection is treatable with oral antimicrobial therapy . AND. the indications and spectrum of activity are identical or similar between alternative drugs

Dec 3, 2024 · Initial presumptive treatment of adult patients with nosocomial pneumonia should start with ZOSYN at a dosage of 4.5 g every six hours plus an aminoglycoside, [totaling 18.0 g (16.0 g piperacillin and 2.0 g tazobactam)], administered by intravenous infusion over 30 minutes.

Jul 12, 2024 · Detailed Piperacillin / Tazobactam dosage information for adults and children. Includes dosages for Bacterial Infection, Skin or Soft Tissue Infection, Pneumonia and more; plus renal, liver and dialysis adjustments.

Mar 1, 2025 · Piperacillin and tazobactam combination is an antibiotic that belongs to the group of medicines known as penicillins and beta-lactamase inhibitors. It works by killing the bacteria and preventing their growth. However, this medicine will not work for …