Enhancer–promoter interactions and transcription are largely
Dec 5, 2022 · We find that enhancer–promoter (E–P) interactions are largely insensitive to acute (3-h) depletion of CTCF, cohesin or WAPL. YY1 has been proposed as a structural regulator …
YY1-controlled regulatory connectivity and transcription are
Aug 29, 2024 · We performed CTCF and RAD21 ChIP–seq and observed 7,931 YY1–RAD21 co-occupied sites (of 41,163 YY1 and 39,745 RAD21 peaks) and 5,968 YY1–CTCF co-occupied …
Enhancer–promoter interactions and transcription are largely …
We find that enhancer–promoter (E–P) interactions are largely insensitive to acute (3-h) depletion of CTCF, cohesin or WAPL. YY1 has been proposed as a structural regulator of E–P loops, …
A prominent and conserved role for YY1 in - Nature
Sep 11, 2014 · YY1 is a multifunctional zinc finger protein that can either activate or repress transcription in a context-dependent manner. Its binding to DNA can be sensitive to DNA …
Prediction of YY1 loop anchor based on multi-omics features
Dec 1, 2024 · The important features predicted for YY1 loop anchor by CHI2 feature selection include: the closest distance between YY1 ChIP-seq peaks and CTCF, SMC3, and RAD21 …
GEO Accession viewer - National Center for Biotechnology Information
Sep 24, 2024 · We performed ChIP-seq (YY1, CTCF, RAD21, LDB1, H3K27ac, and total Pol2) and Micro-C in asynchronous YY1-AID cells treated with auxin for 4h. RNA-seq and TT-seq …
Direct neuronal reprogramming of mouse astrocytes is associated …
Instead, we identified Yy1, a transcriptional co-factor recruited by direct interaction with Ngn2 to its target sites. Upon deletion of Yy1, activation of neuronal enhancers, genes and ultimately …
YY1-controlled regulatory connectivity and transcription are …
Only 0.2% of CRE loops exhibited YY1–RAD21 cobinding at both anchors during the mitosis-to-G1 transition . In sum, we observed concordant YY1 re-occupancy and loop detection at …
Yin Yang 1 regulates cohesin complex protein SMC3 in mouse ...
Jun 25, 2024 · YY1 cooccupies with SMC3 at a large cohort of promoters genome wide and represses SMC3 expression in HSPCs. Establish a distinct regulatory circuit of 2 chromatin …
Epstein–Barr virus nuclear antigen leader protein localizes to ...
Oct 1, 2013 · CTCF is a transcription insulator, which associates with YY1, RAD21, and SMC3 to mediate long-range chromatin interactions (25–38). YY1-associated INO80 chromatin …
- Some results have been removed