Jan 21, 2022 · Herein we describe GUIDE-tag, which enables one-step, off-target genome editing analysis in mouse liver and lung. The GUIDE-tag system utilizes tethering between the Cas9 …

Clustered regularly interspaced palindromic repeats (CRISPR)/Cas9 is a gene-editing technology causing a major upheaval in biomedical research. It makes it possible to correct errors in the …

CRISPR (/ ˈkrɪspər /) (an acronym for c lustered r egularly i nterspaced s hort p alindromic r epeats) is a family of DNA sequences found in the genomes of prokaryotic organisms such as …

原核生物在遭到病毒入侵后，能够把病毒DNA的一小段提取出来并存储到自身基因组上的特定区域， 我们把这个区域称为CRISPR存储空间。 当再次遇到病毒入侵时，原核生物能够根据存储 …

Oct 24, 2013 · Here we describe a set of tools for Cas9-mediated genome editing via nonhomologous end joining (NHEJ) or homology-directed repair (HDR) in mammalian cells, as …

Jul 17, 2024 · 他们成功开发了一站式多重基因组编辑技术—Verispr，极大地促进了用于异种器官移植研究的猪模型的快速生成。 这项在异种器官移植供体猪制备领域具有里程碑意义的研究 …

CRISPR-Cas9 is a genome editing tool that is creating a buzz in the science world. It is faster, cheaper and more accurate than previous techniques of editing DNA and has a wide range of …

Jun 24, 2021 · VISPR-online provides an exploration of screening results and visualization of read count changes. Apart from MAGeCK, VISPR-online supports two more popular CRISPR …

Jul 28, 2021 · A decade ago, the CRISPR/Cas system (also known as the bacterial adaptive immune system) revolutionized genome editing technology.

Dec 19, 2019 · Here we report a multi-functional genome-wide CRISPR (MAGIC) system to precisely control the expression level of defined genes to desired levels throughout the whole …