Lentiviral tropism is determined by the ability of the viral envelope protein to interact with receptors at the host cell surface. The VSV-G envelope protein is commonly used in lentiviral particle production because it confers broad tropism over a range of species and cell types.

Plasmid VSV.G from Dr. Tannishtha Reya's lab contains the insert VSV-G Envelope and is published in Nature. 2003 May 22. 423 (6938):409-14. This plasmid is available through Addgene.

Jul 13, 2018 · Vesicular stomatitis virus G (VSV G) protein is a typical type III viral fusion protein. To study the mechanism of VSV G protein mediated membrane fusion, we set up a cell-cell fusion system in...

Sep 6, 2022 · Vesicular stomatitis virus G glycoprotein (VSV-G) is the most widely used envelope protein for retroviral and lentiviral vector pseudotyping; however, serum inactivation of VSV-G pseudotyped vectors is a significant challenge for in vivo gene delivery.

Jan 9, 2025 · Explore the versatile roles of VSV G protein in viral entry, vaccine development, and gene therapy applications. The vesicular stomatitis virus (VSV) G protein is a key component of the viral envelope, essential for the virus’s ability to infect host cells.

Jan 9, 2025 · Explore the structure and function of VSV-G glycoprotein and its innovative applications in gene therapy and vaccine development. The VSV-G glycoprotein is a component of the vesicular stomatitis virus, playing a role in viral …

Vesicular stomatitis virus G glycoprotein (VSV-G) is the most widely used envelope protein for retroviral and lentiviral vector pseudotyping; however, serum inactivation of VSV-G pseudotyped vectors is a significant challenge for in vivo gene delivery.

Vesicular stomatitis virus glycoprotein G (VSV-G) belongs to a new class of viral fusion proteins (Class III). The structure of VSV-G has been solved in two different conformations and fusion is known to be triggered by low pH.

We have previously shown that vesicles containing the spike glycoprotein of the vesicular stomatitis virus (VSV-G) can associate efficiently with immature, non-infectious, envelope-deficient retrovirus-like particles assembled by packaging cells to produce infectious, pseudotyped viruses in cell-fre …

The spike G glycoprotein of the rhabdovirus vesicular stomatitis virus (VSV-G) is a useful reagent for the study of many aspects of cell biology, including intracellular trafficking of membrane-associated proteins, mammalian cell membrane biogenesis, and the assembly of enveloped mammalian viruses.