Uncaria is a genus of flowering plants in the family Rubiaceae. It has about 40 species. [1] Their distribution is pantropical, with most species native to tropical Asia, three from Africa and the Mediterranean and two from the neotropics. [2] They are known colloquially as gambier, cat's claw or uña de gato. The latter two names are shared ...

Jan 15, 2021 · This review summarizes and discuss the research progress of Uncaria based on alkaloids in the past 15 years, mainly in the past 5 years, including biosynthesis, phytochemistry, pharmacology and structural chemistry.

Jan 15, 2021 · Genus Uncaria from Rubiaceae family is a significant plant source of active alkaloids, with anti-hypertensive, sedative, anti-Alzheimer’s disease, anti-drug addiction and anti-inflammatory effects.

Some in vitro researches presented that Uncaria spp. ameliorate death of neuronal cells, rat cortical neurons, P12 cells, and hippocampal cells induced by amyloid-β, methamphetamine, glutamate, and lipopolysaccharide, respectively (Jung …

Sep 7, 2020 · Cat's claw or ‘Uña de Gato’ is a thick woody vine classified in the Rubiaceae family. For medicinal purposes, the stem bark or root from the species Uncaria tomentosa and U. guianensis are most commonly used.

Here, an integrated evaluation system based on DNA barcoding for species identification and quantitative analysis by LC-MS/MS has been established. DNA barcoding based on the ITS2 barcode region showed sufficient discriminatory power to precisely identify 24 samples from seven Uncaria species.

Jan 1, 2014 · Novel methods of isolation, purification, and structural elucidation of bioactive compounds of Uncaria spp. are highlighted and a discussion on structure–activity relationships is presented. Finally, this chapter attempts to critically analyze the literature to provide a deeper understanding of biological importance of the alkaloids of this genus.

During recent years bioactivity of extracts and pure compounds isolated from Uncaria species have been increasingly investigated. These include anticonvulsive, antiinflammatory, antimutagenic, antioxidant, cytoprotective, hypotensive, and immunoregulatory effects.

May 24, 2023 · Uncaria species are used in traditional medicine and are considered of high therapeutic value and economic importance. This work describes the assembly and annotation of the chloroplast genomes...

The genus Uncaira (Rubiaceae) comprises of 34 species, many of which are usually used as traditional Chinese medicines (TCMs) to treat hypertension, fever, headache, gastrointestinal illness, and fungal infection.