Mar 30, 2025 · UPP1 (Uridine Phosphorylase 1) is a Protein Coding gene. Diseases associated with UPP1 include Long Qt Syndrome and Dihydropyrimidine Dehydrogenase Deficiency. …

Uridine phosphorylase 1 is an enzyme that in humans is encoded by the UPP1 gene. [5] [6] [7] It belongs to the uridine phosphorylase enzyme family.

Feb 8, 2024 · Uridine phosphorylase 1 (UPP1) plays a vital role in uridine metabolism, maintaining homeostasis and aiding pyrimidine salvage 10. It cleaves uridine to uracil and ribose-1 …

May 17, 2023 · Uridine utilization strongly correlated with the expression of uridine phosphorylase 1 (UPP1), which we demonstrate liberates uridine-derived ribose to fuel central carbon …

Oct 1, 2022 · UPP1 overexpression restored lactic acid production and glucose uptake compared to the SGC-CBP30 group. Our findings confirm UPP1 as a novel oncogene in LUAD, thus …

Feb 8, 2024 · Our cytokine array analysis reveals that the upregulation of UPP1 in tumor cells leads to the increased release of various immunosuppressive cytokines, with TGF-β1 being …

UPP1 was significantly upregulated in mesenchymal subtype and could serve as a potential biomarker for this subtype. Based on most correlated genes of UPP1, Gene ontology analysis …

Jan 5, 2021 · The human uridine phosphorylase type 1 (UPP1) is a molecular target of inhibitors proposed to increase Urd levels to prevent adverse effects of chemotherapeutic agents like 5- …

Feb 8, 2025 · Title: UPP1 promotes lung adenocarcinoma progression through the induction of an immunosuppressive microenvironment. Uridine phosphorylase 1 is a novel immune-related …

Jun 24, 2020 · Uridine phosphorylase 1 (UPP1) has been reported as an oncogene in several malignancies. In glioma, the role of UPP1 remains unclear. This study was performed to …