In mitochondria, GABA is converted to succinate through the GABA shunt and ultimately enters the tricarboxylic acid (TCA) cycle or another metabolic pathway to produce γ- hydroxybutyric …

The glyoxylate cycle bypasses the two oxidative decarboxylation reactions of the TCA cycle and directly converts isocitrate through isocitrate lyase and malate synthase into malate and …

Jan 31, 2021 · This work identified that partitioning of flux between the TCA cycle and the glyoxylate shunt combined with a reversible methyl citrate cycle as the critical metabolic nodes …

Sep 9, 2018 · The glyoxylate shunt bypasses the oxidative decarboxylation steps of the tricarboxylic acid (TCA) cycle, thereby conserving carbon skeletons for gluconeogenesis and …

Mitochondrial respiration and tricarboxylic acid (TCA) cycle activity are required during salt stress in plants to provide ATP and reductants for adaptive processes such as ion exclusion, …

Sep 8, 2018 · The aim of this review is to assess how this new knowledge is impacting our understanding of flux control at the TCA cycle/glyoxylate shunt branch point in a wider range …

Mar 1, 2018 · In this study, we balanced the flux distributions between the tricarboxylic acid (TCA) cycle and glyoxylate shunt by optimizing the transcription levels of aceA, aceK and ycdW. …

Nov 1, 2024 · To overcome these limitations, the glyoxylate shunt and reductive TCA pathway were simultaneously enhanced to produce succinate in both aerobic and anaerobic conditions …

Our study reveals that the functional link between the GABA shunt and the TCA cycle operates in both directions. Furthermore, a recent identification of GABA accumulation and its linkage to …

Measurements of CO(2) release, derived from radiolabeled substrates in whole seedlings and in isolated mitochondria, demonstrate impaired GABA-derived input into the TCA cycle, and a …