Sultiame (or sulthiame) is a sulfonamide and inhibitor of the enzyme carbonic anhydrase. It is used as an anticonvulsant and in recent studies showed promise in reducing sleep disordered breathing and other symptoms of obstructive sleep apnea (OSA).

Apr 7, 2022 · In the current four-week, randomized, placebo-controlled, double-blind trial, the investigators observed that those taking sulthiame experienced a clinically relevant OSA improvement—an apnea hypopnea index reduction equal to or greater than 50 percent.

Sultiame is a carbonic anhydrase inhibitor that has been used as an antiepileptic agent in most forms of epilepsy except absence seizures. It may act by lowering the neuronal intracellular pH, thereby reducing the frequency of action potentials in neuronal cells [1, 2].

In this review, we have presented a summary of evidence for the use of STM as monotherapy in epilepsy. To assess the efficacy and side effect profile of STM as monotherapy when compared with placebo or another antiepileptic drug for people with epilepsy.

Sep 15, 2010 · Sulthiame is a carbonic anhydrase inhibitor used primarily in benign focal epilepsies of childhood that may be useful as an adjunct therapy in a variety of other refractory epilepsies. The next evolution of DrugBank is here. Designed for scientists, driven by AI, and powered by real-time insights. This is drug intelligence, redefined.

FRIDAY, Sept. 13, 2024 -- Sulthiame (STM) is beneficial for improving symptoms of obstructive sleep apnea (OSA), according to a study presented at the European Respiratory Society Congress, held from Sept. 7 to 11 in Vienna.

Jan 7, 2025 · Sultiame is a carbonic anhydrase inhibitor used primarily in benign focal epilepsies of childhood that may be useful as an adjunct therapy in a variety of other refractory epilepsies. Sultiame is also used to associated treatment for these conditions: Epilepsy, Rolandic. Take with …

Jan 7, 2025 · Sulthiame is a carbonic anhydrase inhibitor used primarily in benign focal epilepsies of childhood that may be useful as an adjunct therapy in a variety of other refractory epilepsies. Sulthiame is also used to associated treatment for these …

Sultiame (Sulthiame): An antiepileptic medication that works by inhibiting carbonic anhydrase enzymes, used in the treatment of certain types of epilepsy and being studied for other conditions.

Sep 1, 2016 · We report the efficacy of sultiame in treating three children with drug-resistant absence seizures and discuss the potential use of sultiame beyond the idiopathic focal epilepsies.