Mar 27, 2017 · The STIC9 reagent affords the separation of BCR-mediated proliferative signals from TLR9-dependent cell death, thus enabling interrogation of the downstream pathways.

Diagram in B (inset) depicts the structure of STIC9. (E and F) Representative FACS analysis at 60 hours (E) and percentage of live divided cells 60 hours after STIC9 stimulation (F) in C57BL/6 …

switching in STIC9 stimulated cells, and DNA conjugation modulates T-dependent B cell responses in vivo. (A) Sort-purified FO, MZ, TR2/3, and TR1 B cells cultured for 60hrs with …

T-bet upregulation occurs in both murine (Fig. 4) and human (Fig. 5) B cells stimulated with STIC9. These are key findings because T-bet-positive B cells are associated with …

Mar 27, 2017 · We propose that this mechanism integrating BCR, TLR9, and cytokine signals provides a peripheral checkpoint for DNA-containing antigens that, if circumvented by survival …

We propose that this mechanism integrating BCR, TLR9, and cytokine signals provides a peripheral checkpoint for DNA-containing antigens that, if circumvented by survival and …

The STIC9 reagent affords the separation of BCR-mediated proliferative signals from TLR9-dependent cell death, thus RESEARCH ARTICLE enabling interrogation of the downstream …

Oct 21, 2024 · FHWA's STIC Incentive Program will help States foster a culture of innovation and achieve goals to institutionalize innovations. The Technology and Innovation Deployment …

Download scientific diagram | Addition of BLyS prevents AM14 and WT B cells from undergoing proliferation-associated cell death following stimulation with BCR-delivered TLR9 ligands ...

May 5, 2017 · The STIC9 reagent affords the separation of BCR-mediated proliferative signals from TLR9-dependent cell death, thus enabling interrogation of the downstream pathways.