Jan 1, 2011 · Among all types of nanoparticles, biocompatible superparamagnetic iron oxide nanoparticles (SPIONs) with proper surface architecture and conjugated targeting ligands/proteins have attracted a great deal of attention for drug delivery applications.

Superparamagnetic iron-oxide nanoparticles (SPIONs) have unique magnetic properties, due to which they show excellent tumor-targeting efficiency, and this paves the way for effective personalized cancer treatment.

Jun 22, 2023 · The name originates from a battle during the Boer War in South Africa back in 1900, when members of the British army fought to capture a hilltop named Spion Kop – or Spioenkop in Afrikaans.

Superparamagnetic iron oxide nanoparticles (SPION) have been at the forefront of nanotechnology development since the mid-1990s, thanks to their former role as contrast agents for magnetic resonance imaging.

The Battle of Spion Kop (Dutch: Slag bij Spionkop; Afrikaans: Slag van Spioenkop) was a military engagement between British forces and two Boer Republics, the South African Republic and the Orange Free State, during the campaign by the British to relieve the besieged city Ladysmith during the initial months of the Second Boer War.

Feb 7, 2024 · Recently, superparamagnetic iron oxide-based nanoparticles (SPIONs) have emerged as highly effective and efficient for the delivery of therapeutic RNAs to malignant tissues, as well as theranostic (therapy and diagnostic) applications, due to their excellent biocompatibility, magnetic responsiveness, broad functional surface modification, safety...

Superparamagnetic iron oxide nanoparticles (SPION) have a great potential in both diagnostic and therapeutic applications as they provide contrast in magnetic resonance imaging techniques and allow magnetic hyperthermia and drug delivery.

Aug 20, 2017 · Among the various nanoparticles, superparamagnetic nanoparticles (SPIONs) particularly magnetite (Fe 3 O 4) and maghemite (γ-Fe 2 O 3), are researched for their resourcefulness in medical applications like theranostics, hyperthermia, drug delivery, magnet influenced radionuclide therapy, contrasting agents for imaging purposes, and MRI (Schleich...

Feb 17, 2020 · Superparamagnetic iron oxide nanoparticles (SPIONs) have been investigated for wide variety of applications. Their unique properties render them highly applicable as MRI contrast agents, in...

Spion. Iron oxide nanoparticles are iron oxide particles with diameters between about 1 and 100 nanometers. The two main forms are magnetite (Fe3O4) and its oxidized form maghemite (γ-Fe2O3).