Synaptosomal-associated protein 29 is a protein that in humans is encoded by the SNAP29 gene. [5][6][7] This gene, a member of the SNAP25 gene family, encodes a protein involved in multiple membrane trafficking steps.

Nov 13, 2001 · Binding competition studies with SNAP-29 demonstrated that it could compete with α-SNAP for binding to synaptic SNAP receptors (SNAREs) and consequently inhibit disassembly of the SNARE complex.

Mar 30, 2025 · SNAP29 (Synaptosome Associated Protein 29) is a Protein Coding gene. Diseases associated with SNAP29 include Cerebral Dysgenesis, Neuropathy, Ichthyosis, And Palmoplantar Keratoderma Syndrome and Leukodystrophy, Hypomyelinating, 2. Among its related pathways are Innate Immune System and Vesicle-mediated transport.

SNARE-binding protein synaptosomal-associated protein of 29 kDa (SNAP29) regulates the intracellular sequestration of glucose transporter 4 (GLUT4) vesicles in adipocytes. Snapshots from within the cell: Novel trafficking and non trafficking functions of Snap29 during tissue morphogenesis.

Snap29 is a SNARE protein related to Snap25 that gathered a lot of attention in recent years. Here, we review the study of Snap29 and its emerging involvement in autophagy, a self eating process that is key to cell adaptation to changing environments, and in other trafficking pathways.

We isolated a loss of function mutant in Snap29 (Synaptosomal-associated protein 29 kDa), the gene encoding the Drosophila homolog of the human protein SNAP29 and have characterized its function in vivo.

Nov 24, 2014 · Here, we report that O -linked β- N -acetylglucosamine (O -GlcNAc) transferase (OGT) mediates O -GlcNAcylation of the SNARE protein SNAP-29 and regulates autophagy in a nutrient-dependent...

Jun 17, 2024 · SNARE-binding protein synaptosomal-associated protein of 29 kDa (SNAP29) regulates the intracellular sequestration of glucose transporter 4 (GLUT4) vesicles in adipocytes. Snapshots from within the cell: Novel trafficking and non trafficking functions of Snap29 during tissue morphogenesis.

In this study, we demonstrate that the SNARE protein SNAP29 is involved in mast cell phagocytosis. SNAP29 is localized in the endocytic pathway and is transiently recruited to Escherichia coli (E. coli)-containing phagosomes.

Loss of functional SNAP29 results in CEDNIK syndrome (Cerebral Dysgenesis, Neuropathy, Ichthyosis and Keratoderma). Using fibroblast cell lines derived from CEDNIK patients, we show that SNAP29 mediates endocytic recycling of transferrin and β1-integrin.