Oct 1, 2002 · Using p38alpha mitogen-activated protein kinase (MAPK)-deficient cells, we show that the stress-induced phosphorylation of Ser-727 requires p38alpha MAPK activity, whereas …

Our data suggest that STAT1 is phosphorylated at Ser727 by a stress-activated signaling pathway either through p38 MAPK directly or through an unidentified kinase downstream of p38MAPK. …

Here we show that p38 mitogen-activated protein kinase (MAPK), an activator of cPLA (2), is essential for both IFN-alpha and IFN-gamma signalling. SB203580, a specific inhibitor of p38, …

Sep 13, 2002 · Using p38α mitogen-activated protein kinase (MAPK)-deficient cells, we show that the stress-induced phosphorylation of Ser-727 requires p38α MAPK activity, whereas IFN-γ …

Nov 23, 1999 · Our data suggest that STAT1 is phosphorylated at Ser727 by a stress-activated signaling pathway either through p38 MAPK directly or through an unidentified kinase …

Oct 15, 1999 · Here we show that p38 mitogen‐activated protein kinase (MAPK), an activator of cPLA 2, is essential for both IFN‐α and IFN‐γ signalling. SB203580, a specific inhibitor of p38, …

Using p38a mitogen- )sequent su Ser-727 phosphorylation (14). activated protein kinase (MAPK)-deficient cells, we show that the STAT1 can be phosphorylated at Ser-727 independently of …

Our findings collectively indicate that STAT1 signaling modulates intracellular oxidative stress in activated macrophages through a positive-feedback mechanism involving the p38 …

Dec 1, 1999 · Our data suggest that STAT1 is phosphorylated at Ser727 by a stress-activated signaling pathway either through p38 MAPK directly or through an unidentified kinase …

R848 and IFN-a activated p38 MAPK are essential for STAT1-S727 phosphorylation and enhanced B cell responses. (A and B) Splenic B cells were stimulated with IFN-a (1000 U/ml, …