Jul 13, 2017 · What is SLC6A4? The serotonin transporter, encoded by the SLC6A4 gene, is responsible for serotonin reuptake into the presynaptic neuron. While many antidepressants …

Mar 30, 2025 · SLC6A4 (Solute Carrier Family 6 Member 4) is a Protein Coding gene. Diseases associated with SLC6A4 include Obsessive-Compulsive Disorder and Anxiety. Among its …

The gene that encodes the serotonin transporter is called solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 (SLC6A4, see Solute carrier family). In humans the gene is …

May 13, 2019 · Gene-by-environment interactions: Negative life events only lead to depression in individuals with a specific genetic set-up that makes them risk-prone to develop depression. …

We tested the hypothesis that gestational diabetes mellitus alters the DNA methylation pattern of the fetal serotonin transporter gene (SLC6A4), and examined the functional relevance of DNA …

SLC6A4 gene mutation is implicated in acute stress reactivity and response to antidepressants. Learn more about the role of genetic testing for medication.

The human serotonin transporter (SERT) is encoded by a single gene (SLC6A4) located on the long arm of chromosome 17 (17q11-17q12).

In vivo, SLC6A4 variants in humans and other species lead to marked physiological changes, despite mitigating neurodevelopmental adaptations in 5-HT receptors plus compensatory …

Feb 8, 2025 · The serotonin transporter gene (5-HTT/SLC6A4)-linked polymorphic region (5-HTTLPR) is assumed to modulate the interaction between developmental stress exposure and …

Feb 11, 2021 · The serotonin transporter (5-HTT) encoded by SLC6A4 is a key molecule that regulates serotonergic neurotransmission at the synaptic cleft, affecting emotions and stress …