The Crossroads between RAS and RHO Signaling Pathways in …
Ras and Rho proteins are GTP-regulated molecular switches that control multiple signaling pathways in eukaryotic cells. Ras was among the first identified oncogenes, and it appears …
[Research progress of Rho/ROCK signal pathway] - PubMed
This review provides the basic characteristics and physiological effects of Rho/ROCK signal pathway, the relationships between Rho/ROCK signal pathway and diseases, and the …
RhoA/ROCK pathway: implication in osteoarthritis and ... - PubMed
Sep 15, 2019 · RhoA/ROCK interacts with OA pathological factors and induces cartilage degeneration through the degradation of chondrocyte extracellular matrix (ECM). As the …
Rho/ROCK信号通路研究进展 - 仁和软件
Jun 2, 2016 · ROCK又称Rho激酶 (Rho-associated kinase),是目前功能研究最为详细的Rho下游靶效应分子。 Rho/ROCK信号通路诱导细胞骨架重组、细胞迁移和应力纤维形成,与内皮通透性 …
(PDF) Research progress of Rho/ROCK signal pathway
Jun 12, 2016 · Rho GTPases belong to Ras superfamily, which is reported to involve in cell migration, phagocytosis, contraction and adhesion. ROCK (also known as Rho-associated …
Cross‐talk between Ras and Rho signalling pathways in …
We show that the sustained ERK–MAP kinase signalling resulting from transformation by oncogenic Ras down‐regulates ROCK1 and Rho‐kinase, two Rho effectors required for actin …
A focus on Rho/ROCK signaling pathway: An emerging
May 5, 2023 · Rho/Rho-associated coiled-coil containing protein kinase (ROCK) receptors are exclusively expressed in the brain and Rho/ROCK signaling has gained considerable attention …
Rho signaling, ROCK and mDia1, in transformation, metastasis and ...
Jan 22, 2009 · The Rho-ROCK pathway is implicated in Ras-mediated transformation, the amoeboid movement of tumor cells in the three-dimensional matrix, and transmigration of …
Rho/ROCK and MEK/ERK activation by transforming growth factor-
Oct 12, 2009 · Stimulation of EGFR signaling in articular chondrocytes by TGF α resulted in the activation of RhoA/ROCK (Rho kinase), MEK (MAPK/ERK kinase)/ERK (extracellular-signal …
【综述】Ras同源基因家族蛋白A/Rho相关卷曲螺旋蛋白激酶信号通 …
摘要: Ras同源基因家族蛋白A (RhoA)是一种小的鸟苷三磷酸酶蛋白,在缺血性卒中发生发展过程中可激活Rho相关卷曲螺旋蛋白激酶 (ROCK)｡RhoA/ROCK信号通路是缺血性卒中病理过程中 …