Feb 7, 2024 · Rab11a activity is necessary for LC3 positive vesicle emergence at dendritic spines upon simultaneous mTOR inhibition and NMDA treatment. In final series of our experiments, …

Downregulation of Rab8a or Rab11a in SCs reduced the formation of functional TNTs, decreased of vesicle transfer between the connected cells leading to SCs apoptosis and also suppressed …

Ras-related protein Rab-11A is a protein that in humans is encoded by the RAB11A gene. [5][6] The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. It is …

Dec 4, 2022 · In the trans-Golgi network (TGN) Rab11a routes vesicle trafficking between the TGN and ERC or plasma membrane. It plays a vital role in controlling tissue homeostasis …

Rab11 is involved in the transport of several growth factor molecules important for the development and repair of neurons. Overexpression of Rab11 has been shown to significantly …

Sep 28, 2023 · It’s shown that neurons, rather than glial cells, were the primary cell type expressing Rab11a in the spinal dorsal horn (SDH). After intra-plantar injection of CFA, both …

Dec 22, 2016 · Overall, our results suggested that the gene of Rab8a or Rab11a might be involved in the formation of TNTs structures in the peripheral nerve system, while TNTs …

Apr 9, 2018 · RAB11A-positive membranes are a primary direct platform for canonical autophagosome formation that enables autophagy of the transferrin receptor and damaged …

Dec 22, 2016 · Downregulation of Rab8a or Rab11a in SCs reduced the formation of functional TNTs, decreased of vesicle transfer between the connected cells leading to SCs apoptosis …

Jan 30, 2025 · RAB11A and RAB11B exhibit distinct and characteristic distributions in the brain and other organs, suggesting they play different roles throughout the body. In particular, our …