Poloxamers are also known by the trade names Pluronic, [2] Kolliphor (pharma grade), [3] and Synperonic. [4] Because the lengths of the polymer blocks can be customized, many different poloxamers exist that have slightly different properties.

Pluronics, also known as poloxamers, are a class of synthetic block copolymers which consist of hydrophilic poly (ethylene oxide) (PEO) and hydrophobic poly (propylene oxide) (PPO), arranged in an A-B-A triblock structure, thus giving PEO-PPO-PEO …

Pluronic ® PE. The hydrophobic Pluronic ® PE grades are effective foam suppressants. The hydrophilic Pluronic ® PE grades perform well as dispersing agents and emulsifiers. They are supplied in liquid, paste, solid, or powder form, depending on their degree of ethoxylation.

Pluronic ® F-127 is a thermo-reversible gel that finds its application in different industries due to its high thermosensitivity, biodegradability, and biocompatibility properties.

Pluronic block copolymer molecule (A) and micelle with a solubilized drug (B). Pluronic micelles for drug delivery. Incorporation of low molecular mass drugs into Pluronic micelles can increase drug solubility and drug stability, and can improve drug pharmacokinetics and biodistribution.

This mini-review highlights the latest advances in the chemistry and biology of Pluronic® triblock copolymers. We focus on their applications in medicine, as drug delivery carriers, biological response modifiers, and pharmaceutical ingredients.

Nov 22, 2023 · In this review, we have highlighted different types of Pluronic® polymers for prominent photodynamic therapy (PDT) applications. To begin with, we have provided the definition and mechanism of PDT and enumerate its advantages over other frequently used therapeutic modalities.

Pluronics are amphiphilic triblock copolymers composed of two hydrophilic poly (ethylene oxide) (PEO) chains linked via a central hydrophobic polypropylene oxide (PPO). Owing to their low molecular weight polymer and greater number of PEO segments, Pluronics induce micelle formation and gelation at critical micelle concentrations and temperatures.

Aug 1, 2023 · Pluronics copolymers present non-ionic surfactant properties, due to their amphiphilic nature, with high surface activity, good water dispersion, antistatic, and excellent wetting and washing functions.

Mar 17, 2025 · Explore the self-assembly, phase transitions, and material properties of Pluronic F-127, with insights into its responsiveness to pH and temperature changes.