We conclude that the current treatment of protein-losing enteropathy after Fontan operation is associated with a very high mortality and morbidity rate. Preventive strategies and new therapeutic approaches are necessary.

Protein-losing enteropathy (PLE) is a disorder characterized by abnormal and often profound enteric protein loss. It’s relatively uncommon complication of Fontan and other complex congenital heart disease (CCHD) procedures.

Mar 7, 2022 · Protein-losing enteropathy (PLE) represents a rare but severe and potentially life-threatening complication following Fontan operation in patients with a functional single ventricle. PLE is characterized by enteric protein loss, leading to devastating multiorgan involvement with increased morbidity and mortality.

Protein-losing enteropathy (PLE) after the Fontan operation is a serious complication that can be life-threatening. It occurs in at least 10&x0025; of survivors of the Fontan procedure 1 and is thought to be related to increased systemic venous pressure that causes lymphangiectasis and enteric protein loss.

Sep 14, 2007 · Protein-losing enteropathy (PLE) is a poorly understood and enigmatic disease process affecting patients with single ventricle after Fontan operation. In those afflicted, PLE after Fontan operation results in significant morbidity and mortality.

Background: Recent studies have shown that oral budesonide can be used to improve albumin level in patients with protein-losing enteropathy (PLE) following Fontan procedure. However, there has never been a systematic review and meta-analysis to confirm this finding.

Dec 13, 2019 · We review our institutional approach to protein losing enteropathy after Fontan operation and provide a suggested algorithm and pathway for effective care. Protein losing enteropathy (PLE) after Fontan operation is a cruel, challenging condition.

Protein-losing enteropathy (PLE) is a devastating complication after the Fontan operation. This study aimed to investigate the clinical characteristics, treatment response, and outcomes of Fontan-associated PLE. We reviewed the medical records of 38 patients with Fontan-associated PLE from 1992 to 2018 in 2 institutions in Korea.

Jul 25, 2017 · Protein-losing enteropathy (PLE) is a rare and complicated disorder regarding the loss of proteins in the intestines. The signs and symptoms of PLE include bloating, diarrhea, edema, pleural effusions, ascites, and failure to thrive. In some situations, PLE can occur after the Fontan procedure.

Protein-losing enteropathy (PLE) is a poorly understood and enigmatic disease process affecting patients with single ventricle after Fontan operation. In those afflicted, PLE after Fontan operation results in significant morbidity and mortality.