Cytosolic phospholipase A2 is an enzyme that in humans is encoded by the PLA2G4A gene. [5][6] This gene encodes a member of the cytosolic phospholipase A 2 group IV family. The enzyme …

Mar 30, 2025 · PLA2G4A (Phospholipase A2 Group IVA) is a Protein Coding gene. Diseases associated with PLA2G4A include Gastrointestinal Ulceration, Recurrent, With Dysfunctional …

PLA2G4A promotes right-sided colorectal cancer progression by inducing CD39+gammadelta Treg polarization. Inhibition of Cytosolic Phospholipase A2alpha Induces Apoptosis in Multiple …

Activation of PLA2G4A caused LMP and inhibition of autophagy flux in cell lines and primary neurons. In vivo pharmacological inhibition of PLA2G4A attenuated TBI-induced LMP, as well …

Feb 11, 2025 · PLA2G4A promotes right-sided colorectal cancer progression by inducing CD39+gammadelta Treg polarization. Cytosolic Phospholipase A2 Is Required for …

Using an in vitro coculture system and an orthotopic murine model of CRC, we show that the overexpression of Pla2g4a in CT26 cells induced CD39 +γδ Tregs, inhibiting the antitumor …

Mar 7, 2024 · PLA2G4A and ACHE regulated endogenous lipid profile in the platinum resistance in GC patients through the glycerophospholipid metabolism pathway. The screening of lipid …

Phospholipase A2-IVA (PLA2G4A) is the most abundant subtype of cytoplasmic phospholipase A2 (cPLA2) and is an important enzyme in tumor development. Our study aimed to explore the …

Aug 23, 2021 · Using an in vitro coculture system and an orthotopic murine model of CRC, we show that the overexpression of Pla2g4a in CT26 cells induced CD39+γδ Tregs, inhibiting the …

Comparison of LC-MS/MS lysosomal membrane lipid profiles from TBI and sham animals suggested a role for PLA2G4A/cPLA2 (phospholipase A2, group IVA [cytosolic, calcium …