RNA-sequencing analyses indicated that the transcription of most Pi starvation-induced genes is impaired in the phl2 mutant, indicating that PHL2 is also a key component of the central regulatory system. Finally, we showed that PHL2, and perhaps also PHL3, acts redundantly with PHR1 to regulate plant transcriptional response to Pi starvation.

RNA-sequencing analyses indicated that the transcription of most Pi starvation-induced genes is impaired in the phl2 mutant, indicating that PHL2 is also a key component of the central regulatory system. Finally, we showed that PHL2, and perhaps also PHL3, acts redundantly with PHR1 to regulate plant transcriptional response to Pi starvation.

In Arabidopsis (Arabidopsis thaliana), the four transcription factors of the PHOSPHATE RESPONSE 1 (PHR1) family, PHR1 and its homologs PHR1-like 1 (PHL1), PHL2, and PHL3 form the central regulatory system that controls the expression of Pi …

Aug 17, 2021 · Analysis of chromatin accessibility in the phr1 phl2 double mutant revealed that the transcription factors PHR1 and PHL2 play a key role in remodeling chromatin accessibility in response to Pi limitation.

Aug 8, 2021 · This analysis revealed the relative insensitivity to changes in chromatin accessibility in response to Pi limitation in the phr1 phl2 double mutant (Fig. 6A), as evidenced by our identification of 1,942 upDARs (34% of WT) and 155 downDARs (13% of …

Aug 18, 2016 · PHO2 has been demonstrated to regulate Pi uptake in roots and Pi translocation from roots to shoots by mediating protein degradation of high-affinity Pi transporters and PHOSPHATE1 (PHO1) [25, 26].

Nov 19, 2015 · RNA-seq analyses indicated that the transcription of most Pi starvation-induced genes is impaired in the phl2 mutant, indicating PHL2 is also a key component of the central regulatory system....

Nov 14, 2022 · Among PHR1 and homologues, PHR1 and PHL2 are the key factors regulating the accessibility of chromatin of PSR genes under Pi-limited conditions (Barragán-Rosillo et al., 2021). Arabidopsis and rice contain 4 (AtSPX1–SPX4) and 6 …

Apr 19, 2024 · In this PHR1 family, PHR1/PHR1-like 1(PHL1) and PHL2/PHL3 form two distinct modules in regulating plant development and transcriptional responses to Pi starvation. PHL4 is the most closely related member to PHR1.

Nov 19, 2019 · We found that the 5′-UTR of PHO2 contains two PHR1 binding sites (P1BSs) and one Pi-responsive PHO element. Using a yeast one-hybrid (Y1H) assay, we identified two candidate proteins that might mediate this transcriptional regulation: a barley PHR1 ortholog and a TF containing an uncharacterized MYB domain.