Pepstatin is a potent inhibitor of aspartyl proteases. It is a hexa-peptide containing the unusual amino acid statine (Sta, (3S,4S)-4-amino-3-hydroxy-6-methylheptanoic acid), having the …

Pepstatin A is a pentapeptide isolated from Streptomyces testaceus. It is a potent inhibitor of aspartyl proteases. It has a role as a bacterial metabolite and an EC 3.4.23.* (aspartic …

Pepstatin is a low molecular weight, potent inhibitor specific for acid proteases with a Ki value of about 10(-10)M for pepsin. The chemical structure of pepstatin is essentially a hexapeptide …

Pepstatin A is a microbial hexapeptide produced by Actinomycetes spp. and a potent inhibitor of almost all types of aspartic proteases, including SAPs . This inhibitor modulates virulence of …

Pepstatin is a low molecular weight, highly specific inhibitor of acid proteases, in particular aspartate proteases. It has been shown to inhibit virtually all acid proteases including pepsin, …

Pepstatin, discovered around 1970, was found to strongly inhibit pepsin and other members of the aspartic protease family. This compound is a relatively nonspecific inhibitor, as it seems to …

Pepstatin A is an inhibitor of acid proteases (aspartyl peptidases). It forms a 1:1 complex with proteases such as pepsin, renin, cathepsin D, bovine chymosin, and protease B (Aspergillus …

Jan 1, 2012 · Pepstatin is a strong inhibitor for all acid proteases. It does not inhibit other groups of proteases, such as the neutral and alkaline proteases (1). The unusual potency of pepstatin …

Pepstatin A is an inhibitor of aspartic acid protease. It is highly selective without inhibiting thiol proteases, neutral proteases or serine proteases.

5 days ago · Pepstatin A treatment of osteoclast cells suppressed receptor activator of NF-κB ligand (RANKL)-induced differentiation to mononuclear osteoclast cells by blocking NFATc1 …