Rolicyclidine (PCPy) is a dissociative anesthetic that is similar in effects to phencyclidine, but is slightly less potent and has fewer stimulant effects. [2] It instead produces a sedative effect described as being somewhat similar to a barbiturate, but with additional PCP-like dissociative, anaesthetic and hallucinogenic effects. [3]

Rolicyclidine (PCPy) is classified as a dissociative anesthetic agent. It also has hallucinogenic and sedative properties. Because of its pharmacodynamic similarity to the drug phencyclidine (PCP), rolicyclidine was added to the Schedule I list of illegal drugs in the USA in the 1970s.

3-Methyl-PCPy (3-Me-PCPy) is an arylcyclohexylamine derivative with an unusual spectrum of pharmacological effects, acting as both a potent NMDA antagonist and also a triple reuptake inhibitor which inhibits reuptake of all three monoamine neurotransmitters serotonin, dopamine and noradrenaline.

Jul 31, 2007 · Rolicyclidine (PCPy) is classified as a dissociative anesthetic agent. It also has hallucinogenic and sedative properties. Because of its pharmacodynamic similarity to the drug phencyclidine (PCP), rolicyclidine was added to the Schedule …

Rolicyclidine (also known as PCPy, or sometimes PHP) is a simple dissociative substance of the arylcyclohexylamine class. Compared to plain PCP, it is almost unknown, despite a strikingly easier synthesis, employing unwatched pyrrolidine instead of piperidine.

Phencyclidine-type substances show structural similarity to phencyclidine (PCP) and ketamine and are classified as arylcycloalkylamines.[1] PCP was first synthesized in the 1950s and sold until 1967 as an injectable anaesthetic in the United …

3-Methoxyphencyclidine (3-MeO-PCP) and 3-methoxyrolicyclidine (3-MeO-PCPy) are two new psychoactive substances (NPS). The aims of the present study were the elucidation of their metabolic fate in rat and pooled human liver microsomes (pHLM) the ...

Aug 14, 2018 · PCP soon became the prototypical dissociative agent that eventually sneaked through the doors of clinical laboratories and became an established street drug. Estimations suggest that around 14 PCP analogs were identified as “street drugs” in the period between the 1960s and 1990s.

Rolicyclidine (PCPy) is a dissociative anesthetic drug with hallucinogenic and sedative effects.

Classic examples of psychoactive arylcycloalkylamines include ketamine and 1- (1-phenylcyclohexyl)piperidine (PCP) and many others serve as important structural templates for neuropharmacological research.