The periaqueductal gray (PAG), also known as the central gray, is a brain region that plays a critical role in autonomic function, motivated behavior and behavioural responses to …

Nov 11, 2021 · All these three areas, together with neurons in the medial preoptic area (MPA) 17, target neurons in the periaqueductal gray matter (PAG) to exert their function, suggesting that …

Jul 24, 2023 · The periaqueductal gray (PAG) is a key structure in the propagation and modulation of pain, sympathetic responses as well as the learning and action of defensive and …

Taken together, our findings establish that PAG-USV neurons provide an essential and selective pathway for vocal control in the mouse, affording an entry point for genetically dissecting the …

Aug 7, 2019 · Here, we used an intersectional genetic method to label and manipulate neurons in the midbrain periaqueductal gray (PAG) that are transiently active in male mice when they …

May 10, 2019 · The rostrolateral PAG, most often defined at the level of the oculomotor nucleus, has emerged as an area that is critical for predatory behaviors in cats, rats and mice (Shaikh …

Recent advances in neural circuitry techniques, like optogenetics and chemogenetics, have allowed for a greater understanding of the periaqueductal gray (PAG) and its importance in …

The recent identification of specialized neurons in the caudolateral PAG whose activity is important for the production of male mouse courtship ultrasonic vocalizations (USVs) (PAG …

Jan 24, 2018 · Here, we show that activating vlPAG GABAergic neurons in mice suppresses the initiation and maintenance of REM sleep while consolidating NREM sleep, partly through their …

Apr 9, 2025 · Thanks to a mouse watching clips from "The Matrix," scientists have created the largest functional map of a brain to date -- a diagram of the wiring connecting 84,000 neurons …