
Overview of Prostate-Specific Membrane Antigen - PMC
Results showed naked mAbs induced antibody-dependent cell-mediated cytotoxicity of human prostate cells; the mAb labeled with isotope 177 Lu was well tolerated and was effective in …
PSMA redirects cell survival signaling from the MAPK to the PI3K …
Increased abundance of the prostate-specific membrane antigen (PSMA) on prostate epithelium is a hallmark of advanced metastatic prostate cancer (PCa) and correlates negatively with …
Biological determinants of PSMA expression, regulation and ...
Jul 8, 2024 · Prostate-specific membrane antigen (PSMA) is an important cell-surface imaging biomarker and therapeutic target in prostate cancer. The PSMA-targeted theranostic 177 Lu …
[68Ga]Ga-PSMA-11 in prostate cancer: a comprehensive review
Expression of prostate-specific membrane antigen (PSMA), increases cell folate uptake and proliferation and suggests a novel role for PSMA in the uptake of the non-polyglutamated …
PSMA: A New Target for Prostate Cancer Treatment
Nov 15, 2017 · Prostate cancer cells have high levels of prostate-specific membrane antigen (PSMA), but researchers were unsure of its biological role. Now an MSK-led team has …
Novel Role of Prostate-Specific Membrane Antigen in Suppressing ...
Feb 10, 2005 · Prostate-specific membrane antigen (PSMA), a type II transmembrane glycoprotein, is overexpressed in prostate cancer. PSMA is a unique cell surface marker, …
Tumor target prostate specific membrane antigen (PSMA) and its ...
Feb 15, 2004 · PSMA can serve as target for delivery of therapeutic agents such as cytotoxins or radionuclides. PSMA has two unique enzymatic functions, folate hydrolase and NAALADase …
Levels of PSMA and Numbers of Positive Cells Determine Success …
Jul 31, 2020 · Prostate-specific membrane antigen (PSMA) is a cell surface molecule expressed at variable levels by advanced, castration-resistant prostate cancer cells. PSMA drives cancer …
Prostate Specific Membrane Antigen - ScienceDirect
Prostate-specific membrane antigen (PSMA) is a membrane-bound antigen that is highly specific for benign and malignant prostatic epithelial cells. 27–36 It is present in the serum of normal …
Prostate-Specific Membrane Antigen–Targeted Therapies for …
Mar 1, 2024 · Prostate-specific membrane antigen (PSMA) is a transmembrane glycoprotein overexpressed in most prostate cancers and exploited as a target for PSMA-targeted …
- Some results have been removed