Protein arginine methyltransferase 5 - Wikipedia
PRMT5 is a highly conserved arginine methyltransferase that translocated from the cytoplasm to the nucleus at embryonic day ~E8.5, and during preimplantation development at the ~4-cell …
PRMT5 function and targeting in cancer - PubMed
Jul 13, 2020 · Here we discuss the function of PRMT5, a member of the nine-member PRMT family, in controlling oncogenic processes including tumor intrinsic, as well as extrinsic …
A review of the known MTA-cooperative PRMT5 inhibitors - PMC
Protein arginine methyltransferase 5 (PRMT5), an epigenetic target with significant clinical potential, is closely associated with the occurrence and development of a range of tumours …
The PRMT5 arginine methyltransferase: many roles in …
Post-translational arginine methylation is responsible for regulation of many biological processes. The protein arginine methyltransferase 5 (PRMT5, also known as Hsl7, Jbp1, Skb1, …
PRMT5 Gene - GeneCards | ANM5 Protein | ANM5 Antibody
Mar 30, 2025 · PRMT5 (Protein Arginine Methyltransferase 5) is a Protein Coding gene. Diseases associated with PRMT5 include Sarcomatoid Transitional Cell Carcinoma and Esophageal …
Discovery of a Potent and Selective Protein Arginine …
4 days ago · Protein arginine methyltransferase 5 (PRMT5) plays crucial roles in the regulation of various biological processes through the mono- and symmetric dimethylation of protein …
PRMT5 is an actionable therapeutic target in CDK4/6 inhibitor
Mar 13, 2024 · Through a genome-wide CRISPR screen, we identify protein arginine methyltransferase 5 (PRMT5) as a molecular vulnerability in ER+/RB1-knockout breast cancer …
PRMT5 protein arginine methyltransferase 5 [ (human)]
Feb 9, 2025 · PRMT5 knockdown enhances cell viability and suppresses cell apoptosis, oxidative stress, inflammation and endothelial dysfunction in ox-LDL-induced vascular endothelial cells …
Targeting protein arginine methyltransferase 5 in cancers: Roles ...
Dec 1, 2021 · Recently, increasing evidence has demonstrated that PRMT5 plays an indispensable role in the occurrence and development of various human cancers by promoting …
PRMT5: a putative oncogene and therapeutic target in prostate cancer
Apr 14, 2021 · In this review, we focus on recent progress made in prostate cancer, including the role of PRMT5 in the androgen receptor (AR) expression and signaling and DNA damage …
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