There are significant differences in the amounts of GFs produced using the three different APC techniques (CGF, PRF and PRP). PRF and CGF produce significantly more GFs during the procedure as compared to PRP. The levels of bFGF in …

Nov 5, 2023 · PRF （Platelet-RichFibrin，富血小板纤维蛋白） 它是 2000年报道的第二代富血小板血液制品，它的制备方法是通过全血不添加任何抗凝剂立刻一次离心而获得的高浓度血小板纤维蛋白凝胶。 它制备简单无需任何生物添加剂的处理，在PRF通过离心分离的制备过程中血小板被激活同时大量脱颗粒细胞中蕴含的重要的生长因子释放出来。 CGF （Concentrate growth factors，浓缩生长因子） 它是2006 年提出第 3 代富血小板血液制品，该制品由不含抗凝剂的 …

Mar 23, 2022 · For this purpose, in this study, PPP, CGF and PRF were applied to rabbit extraction sockets to observe and compare their effects on wound healing and alveolar bone resorption in order to identify more appropriate options for filling extraction sockets and to develop new clinical treatment methods.

Platelet rich fibrin (prf), concentrated growth factor (cgf) and sticky bone: These are second generation platelet aggregates. Prf: It was first developed by Choukroun in france in 2001.

Mar 23, 2022 · CGF showed more effective bone induction and tissue regeneration ability in the long term. In conclusion, the application of PRF, CGF and PPP in tooth extraction sockets effectively promoted bone regeneration.

Fibrin clot membranes prepared from advanced platelet-rich fibrin (A-PRF) or concentrated growth factors (CGF), despite their relatively rapid biodegradability, have been used as bioactive barrier membranes for alveolar bone tissue regeneration.

Apr 10, 2021 · Overall, PRP is mainly used in cases of hard and soft tissue procedures, while PRF is used in gingival recession and the treatment of furcation and intrabony defects; CGF is mainly used in bone regeneration.

Upon contact with exposed endothelium (due to damage tissue or wound) the platelets get activated and are known to release key wound healing factors: Platelet derived growth factor (PDGF), vascular endothelial growth factor (VEGF), transforming growth factor (TGF) and epidermal growth factor (EGF).

CGF stands for Concentrate-Growth-Factors and, like PRF, does not require the addition of bovine thrombin or any anticoagulant. CGF uses a variable speed of 2400-2700 rpm to separate cells from venous blood, resulting in larger, denser, growth factor-rich fibrin clots than even conventional PRF.

Overall, PRP is mainly used in cases of hard and soft tissue procedures, while PRF is used in gingival recession and the treatment of furcation and intrabony defects; CGF is mainly used in bone regeneration. Keywords:PRP; PRF; CGF; facial rejuvenation; autologous platelet concentrates; periodontal regeneration.