Appropriate indications for PPI use include Helicobacter pylori infection, erosive esophagitis, gastric ulcers, and stress ulcer prevention in high-risk critically ill patients. Unfortunately, PPIs …

Sep 28, 2023 · Proton pump inhibitors (PPIs) are a group of medicines that decrease stomach acid production. They can help relieve symptoms of chronic acid reflux (GERD) and stomach …

The purpose of this review is to evaluate the risks associated with long-term use of proton pump inhibitors (PPIs), focusing on long-term use of PPIs for three common indications: …

Oct 11, 2024 · People with GERD may rely on a proton pump inhibitor (PPI), a type of medication that lowers stomach acid production; common ones include omeprazole (Prilosec®), …

Numerous types of side effects of PPIs have been proposed and we have in this review focused on the increased risk of gastric neoplasia, kidney disease, bone fractures, impaired absorption …

Patients have experienced few minor side effects of short-term PPI use, such as headache, rash, dizziness, and gastrointestinal symptoms including nausea, abdominal pain, flatulence, …

Feb 1, 2018 · A recent meta-analysis of 18 observational studies revealed that PPI use was associated with a 33% increased risk for fracture at any site (RR, 1.33; 95% CI, 1.15-1.54), a …

May 31, 2024 · Proton pump inhibitors (PPIs) effectively block gastric acid secretion by irreversibly binding to and inhibiting the hydrogen-potassium ATPase pump that resides on the …

Apr 5, 2024 · Here's a rundown of the some of the side effects that are causing concern: Fracture risk. Some studies have shown an association between PPIs and the risk of fracture — …

Oct 23, 2024 · While most of the side effects are mild and manageable, there are a number of adverse events which can occur with long-term use or overuse. These include problems with …