Aug 8, 2014 · Actually, the doctor needs to know what the patient's normal heart rate is in order to form a valid opinion. For a lot of people, 70 beats per minute would be ok, but for someone like me, with a normal resting pulse of 52, a pulse rate of 70 is 30% up on 'my' normal, and probably means I am unwell. I think the same logic applies to the P1NP test.

May 20, 2020 · I assume, since you have had the bone marker tests, CTX and P1NP, that you have been seen by a bone specialist. You do not have severe osteoporosis because you mentioned that you have had no fractures. Severe osteoporosis is defined as T-score below -2.5 AND the presence of one or more fragility fractures.

Jun 6, 2020 · hello Buddy, this is what i mean: "In 15 studies, the mean/median reference intervals for P1NP in premenopausal women ranged between 33.0 µg/L and 47.7 µg/L 27, 29-31, 33-41, 49, 50; similarly, in 8 studies, the mean/median reference intervals for P1NP in adult men ranged between 32.7 µg/L and 64.9 µg/L34-36, 38, 42-45."

Feb 1, 2024 · P1NP measures the bone formation and CTX (aka BetaCrosslaps) the bone resorption. P1NP is for monitoring anabolic drug (teriparatide, Tymlos, Evenity). It is not essential, mostly a yearly DXA is enough. Either they work or not, and we don't know why.

Aug 4, 2010 · Increases of P1NP and P1CP while taking Forteo correlated best with increases in Lumbar spine BMD and reduced fracture risk. Now if you aren't taking any of these meds, the question would be, what raised the formation marker and your doctor should know this.

Jun 17, 2022 · P1NP is a blood bone marker for bone formation. The higher the number, the higher the bone formation. CTX is a blood bone marker for bone resorption. The higher the number, the higher the bone resorption. Bone markers have a range depending on bone drug or no drug, age (before or after menopause), sex, ... You should ask your doctor.

Apr 15, 2021 · After about 3 months of daily dosing with Forteo, the P1NP or BSAP is high, and most patients start to show an initial increase in osteoclastic bone resorption (fasting CTx or urine NTx). After 9-12 months of daiky Forteo, most patients will show a greater increase from baseline in bone resorption marker vs bone formation marker.

Nov 8, 2023 · Ideally, you need a baseline of bone markers (P1NP for bone formation and CTx for bone resorption) after correcting vitamin D3, calcium, etc, before starting Forteo. After 3 months on Forteo, P1NP and CTx again... Without bone markers, you have the DXA (or REMS) yearly, because you are on an anabolic drug.

Feb 14, 2021 · 2) My 22% gain in P1NP at two months looks meager next to study participants nearly 100% gain at three months. 3) Their average CTX was a little higher and P1NP a little lower than mine was at diagnosis when I had recent fractures and was presumed to be losing bone overall. 4) The variation among participants is huge.

Apr 14, 2021 · The Bone Health and Osteoporosis Foundation Support Community connects patients, families, friends and caregivers for support and inspiration.