May 15, 2024 · Myeloid-derived suppressor cells (MDSCs) are known to suppress antitumor immune responses, and the effect of natural killer (NK) cells on their development has been …

This review discusses MDSC-mediated NK cell regulation within the TME, focusing on critical cellular and molecular interactions. We review current strategies that target MDSC-mediated …

NK cells have been shown to play a fundamental role in haploidentical hemopoietic stem cell transplantation (HSCT), for the therapy of high-risk leukemias. A deeper analysis of MDSC …

Jul 1, 2022 · This review discusses MDSC-associated immunosuppression, the mechanisms regulating communication between MDSCs and NK cells in the tumor microenvironment, and …

May 15, 2024 · Apart from their killer identity, natural killer (NK) cells have integral roles in shaping the tumor microenvironment. Through immune gene deconvolution, the present study …

Cryo-thermal therapy induces effective CD4 + Th1-dominant antitumor immunity by activating NK cells to reprogram MDSCs, providing a promising therapeutic strategy for cancer immunotherapy.

Natural killer (NK) cells can engage in crosstalk with multiple myeloid cells to alter adaptive immune responses, triggering T-cell immunity. However, whether the NK-cell-MDSC …

May 8, 2014 · CD16xCD33 BiKE potently activates blood and marrow MDS-NK cells at all diseases stages to lyse CD33 + MDS and CD33 + MDSC targets. Myelodysplastic syndromes …

Here, we review whether the crosstalk between MDSCs and NK cells can impact on tumor onset, angiogenesis and progression, focusing on key cellular and molecular interactions.

Feb 12, 2021 · NK cells have been shown to play a fundamental role in haploidentical hemopoietic stem cell transplantation (HSCT), for the therapy of high-risk leukemias. A deeper …