Stromelysin-1 also known as matrix metalloproteinase-3 (MMP-3) is an enzyme that in humans is encoded by the MMP3 gene. The MMP3 gene is part of a cluster of MMP genes which localize …

Matrix metalloproteinase 3 (MMP-3) is a member of the matrix metalloproteinase (MMP) family, which can degrade multiple ECM components. MMP-3 can activate multiple pro-MMPs and …

Matrix metalloproteinase-3 (MMP-3) plays an important role in the pathology of rheumatoid arthritis (RA) and ankylosing spondylitis (AS). Measurement of active MMP-3 in clinical …

Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that belong to the metzicin superfamily and are involved in the degradation and remodeling of extracellular matrix (ECM) …

Oct 29, 2010 · MMP-3 activity is regulated at three different levels: gene expression, proteolytic activation of the zymogen, and inhibition by the endogenous tissue inhibitors of …

Apr 7, 2025 · Serum matrix metalloproteinase 3 is an independent predictor of structural damage progression in patients with ankylosing spondylitis. Maksymowych WP, et al. Arthritis Rheum, …

MMP-3 is a significant independent predictor of radiographic progression in patients with ankylosing spondylitis, particularly in those with preexisting radiographic damage. induction in …

Serum level of MMP-3 appear to be an useful marker in the diagnosis of rheumatoid arthritis and also for the evaluation of prognosis of joint destruction and cartilage degradation. Increased …

Apr 19, 2023 · Here, we report the development of an AAV-delivered enzyme, i.e., matrix metalloproteinase-3 (MMP-3), that can efficiently increase outflow facility in the nonhuman …

Matrix metalloproteinase-3 or MMP3 also known as stromelysin-1 is an enzyme that is actively involved in joint destruction in rheumatoid arthritis (RA) patients. Screening the last three …