MAX (also known as myc-associated factor X) is a gene that in humans encodes the MAX transcription factor. [5][6] The protein product of MAX contains the basic helix-loop-helix and …

Mar 30, 2025 · MAX (MYC Associated Factor X) is a Protein Coding gene. Diseases associated with MAX include Pheochromocytoma and Polydactyly-Macrocephaly Syndrome. Among its …

Jul 1, 2012 · MYC-associated protein X (MAX) is a ubiquitous, constitutively expressed protein that plays a central role in controlling the MYC/MAX/MAX dimerization protein 1 (MXD1) axis, …

May 14, 2012 · Recently we identified germline mutations in a new tumor suppressor susceptibility gene, MAX (MYC-associated factor X), which predisposes carriers to PCC. How MAX …

May 28, 2020 · Our genomic occupancy and gene expression studies reveal that MAX and MNT repress multiple genes, including those involved in the 1C pathway, which may contribute to …

If you have a mutation in the MAX gene, this means you have a condition called hereditary paraganglioma-pheochromocytoma (PGL/PCC) syndrome. MAX mutations increase your risk …

Mar 25, 2021 · Germline MAX mutations are associated with PCs, ganglioneuromas, neuroblastomas, pituitary neuroendocrine tumors, and, possibly, parathyroid adenomas, as …

HGNC Approved Gene Symbol: MAX. Cytogenetic location: 14q23.3 Genomic coordinates (GRCh38) : 14:65,006,101-65,102,695 (from NCBI)

Context: MYC-associated factor X (MAX) has been recently described as a new susceptibility pheochromocytoma (PHEO) gene with a total of ~40 reported cases. At present, no study has …

The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with …