Matrix metalloproteinase-9 (MMP-9), also known as 92 kDa type IV collagenase, 92 kDa gelatinase or gelatinase B (GELB), is a matrixin, a class of enzymes that belong to the zinc - metalloproteinases family involved in the degradation of the extracellular matrix.

As one of the most widely investigated matrix metalloproteinases (MMPs), MMP-9 is a significant protease which plays vital roles in many biological processes. MMP-9 can cleave many extracellular matrix (ECM) proteins to regulate ECM remodeling. It ...

Matrix metalloproteinase (MMP)-9, one of the most widely investigated MMPs, regulates pathological remodeling processes that involve inflammation and fibrosis in cardiovascular disease. MMP-9 directly degrades extracellular matrix (ECM) proteins and activates cytokines and chemokines to regulate tissue remodeling.

Jul 9, 2021 · Matrix metalloproteinase (MMP)-9, one of the most widely investigated MMPs, regulates pathological remodeling processes that involve inflammation and fibrosis in cardiovascular disease. MMP-9 directly degrades extracellular matrix (ECM) proteins and activates cytokines and chemokines to regulate tissue remodeling.

MMP-9, a member of the gelatinase B family, is characterized as one of the most intricate MMPs. The crucial involvement of MMP-9 in extracellular matrix (ECM) remodeling underscores its significant correlation with each stage of cancer pathogenesis and progression.

May 15, 2020 · Matrix metalloproteinases (MMPs) are zinc dependent proteolytic metalloenzyme. MMP-9 is one of the most complex forms of matrix metalloproteinases. MMP-9 has the ability to degrade the extracellular matrix (ECM) components and has important role in the pathophysiological functions.

Jan 4, 2025 · Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis.

MMP-9, also known as gelatinase B, is an enzyme belonging to the family of matrix metalloproteinases (MMPs) that specifically targets the degradation of type-IV collagen, laminin, and fibronectin, which are essential components of the basal membrane and cerebral blood vessels. You might find these chapters and articles relevant to this topic.

Know comprehensive MMP-9 protein information including protein sequence, molecular weight, theoretical pI, structure, function and protein interaction.

MMP9 is a multidomain protein with a molecular weight of 92 kDa, capable of catalyzing the degradation of large extracellular matrix (ECM) components such as elastin and collagen and specific cell surface proteins.