Mannan-binding lectin serine protease 1 also known as mannose-associated serine protease 1 (MASP-1) is an enzyme that in humans is encoded by the MASP1 gene. [5] [6] [7] MASP-1 is …

The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. …

Dec 25, 2024 · MASP1 (MBL Associated Serine Protease 1) is a Protein Coding gene. Diseases associated with MASP1 include 3Mc Syndrome 1 and 3Mc Syndrome. Among its related …

The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2. Functions …

Human MBL forms complexes with two types of serine proteases termed MASP (MBL-associated serine protease). These two proteases, MASP1 and MASP2, are structurally similar to one …

Feb 11, 2017 · MASP1 and MASP2 are two genes encoding mannose-binding lectin-associated serine proteases (or MASPs) and truncated mannose-binding lectin-associated proteins (MAps).

novel 45-kDa serum protein derived from the MASP1 gene, which is highly expressed in striated muscle tissues and is found in complex with MBL and ficolins and may function as a potent …

Dec 10, 2024 · The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it …

Three proteins are produced from the MASP1 gene: MASP-1 and MASP-3 and MAp44. We present an assay specific for MASP-1, which is based on inhibition of the binding of anti-MASP …

Jun 19, 2013 · The deduced 728-amino acid MASP3 protein has a signal peptide, 3 N-glycosylation sites on the B chain and 4 on the A chain. Sirmaci et al. (2010) stated that the …