Letrozole (Femara) Letrozole is a type of hormone therapy drug. It is also known as Femara. It is a treatment for breast cancer. Letrozole is pronounced let-roe-zole. How does letrozole work? Letrozole lowers the levels of the female sex hormone oestrogen in the body. Oestrogen stimulates some breast cancers to grow.

taking tamoxifen for 5 years and then letrozole for a further 5 years; Your doctor will think about your general health and possible side effects of the drugs when deciding which hormone treatment will be best for you. You might have aromatase inhibitors in combination with other drug treatments such as: palbociclib; alpelisib; ribociclib ...

Jan 7, 2025 · letrozole; trastuzumab; tucatinib; Palbociclib is a targeted drug called a cancer growth blocker. It works by blocking 2 proteins on the cancer cells. By blocking these proteins, it can slow down or stop the cancer cells from growing. Doctors already use palbociclib to treat breast cancer that has spread. Letrozole is a hormone therapy. It ...

Jan 29, 2018 · And research had shown that having letrozole for another 5 years, after the first 5 years of hormone therapy, may further reduce the risk of the cancer coming back. The results of a small study had shown that having intermittent letrozole may be as good as, or even better than, having it continuously.

Nov 21, 2016 · 89 women who were taking letrozole took part in this study. Before starting letrozole, the women had a sample of their breast cancer tissue (a biopsy) taken. They had another biopsy 2 weeks and 3 months after starting treatment. Researchers looked at the changes in the genes of the cancer tissue. They identified changes in 4 genes.

Letrozole and megestrol acetate are tablets that you take every day, once a day. You swallow them whole, with or without food. You take letrozole, or letrozole and megestrol acetate, for up to 19 days until the morning of your operation. Then everyone has surgery to remove the breast cancer. This is the same as the standard treatment.

Mar 2, 2018 · Ribociclib and letrozole are both tablets. You take: 3 tablets of ribociclib once a day for 21 days; 1 tablet of letrozole once a day for 28 days; Men and pre menopausal women have goserelin or leuprorelin as an injection. You have this as an injection just under the skin (a subcutaneous injection), usually into your tummy.

103 had letrozole on its own; 68 had letrozole for 2 weeks followed by letrozole and palbociclib for the next 12 weeks; 69 had palbociclib for 2 weeks followed by letrozole and palbociclib for the next 12 weeks; 67 letrozole and palbociclib for 14 weeks; For every 3 women in group A, there were 2 women in group B, group C or group D.

Some post menopausal women with breast cancer take aromatase inhibitors instead of tamoxifen. Examples of aromatase inhibitors include anastrozole (Arimidex) or letrozole (Femara). These medicines also lower levels of oestrogen, which can reduce sexual desire. Aromatase inhibitors may have side effects such as fatigue and depression.

In step 1 everyone takes letrozole or anastrozole with either abemaciclib, palbociclib or ribociclib. You give a blood sample every 8 to 12 weeks. The team use the blood samples to look for the gene change (mutation) in ESR1. They do this by looking for small pieces of the cancer DNA (ctDNA) in the blood.