Mar 30, 2025 · LMX1B (LIM Homeobox Transcription Factor 1 Beta) is a Protein Coding gene. Diseases associated with LMX1B include Nail-Patella Syndrome and Focal Segmental Glomerulosclerosis 10. Among its related pathways are Genes controlling nephrogenesis and Dopaminergic neurogenesis.

LIM homeobox transcription factor 1-beta, also known as LMX1B, is a protein which in humans is encoded by the LMX1B gene. [5][6] LMX1B is a LIM homeobox transcription factor which …

Lmx1b is a homeodomain transcription factor required for glomerular basement membrane collagen expression by podocytes. Its absence in nail-patella syndrome causes abnormalities in many organ systems.

The LMX1B gene provides instructions for producing a protein that attaches (binds) to specific regions of DNA and regulates the activity of other genes. Learn about this gene and related health conditions.

LIM-homeodomain proteins are characterized by the presence of 2 tandem cysteine/histidine-rich, zinc-binding LIM domains. LMX1 (600298), a LIM-homeodomain-containing protein expressed selectively in insulin-producing beta cell lines, has been shown to …

Aug 3, 2003 · Our results suggest that, during development of 5-HT neurons, Lmx1b is a critical intermediate factor that couples Nkx2-2–mediated early specification with Pet1-mediated terminal differentiation.

LMX1B is a LIM-homeodomain transcription factor required for the normal development of dorsal limb structures, the glomerular basement membrane, the anterior segment of the eye, and dopaminergic and serotonergic neurons.

Feb 8, 2025 · It functions as a transcription factor, and is essential for the normal development of dorsal limb structures, the glomerular basement membrane, the anterior segment of the eye, and dopaminergic and serotonergic neurons. Mutations in this …

Jan 4, 2025 · It functions as a transcription factor, and is essential for the normal development of dorsal limb structures, the glomerular basement membrane, the anterior segment of the eye, and dopaminergic and serotonergic neurons. Mutations in this …

Lmx1b is a LIM homeodomain transcription factor that has been implicated in the development of several neuronal systems, such as the serotonin-containing raphe nuclei (e.g. Zhao et al., 2006). Here, we show that in mouse embryonic development, Lmx1b is …