Epstein–Barr virus latent membrane protein 1 (LMP1) is an Epstein–Barr virus (EBV) protein that regulates its own expression and the expression of human genes. [1] . It has a molecular …

Latent membrane protein 1 (LMP1) is considered to be the main EBV oncogene. Its potential to transform cells was first discovered by Wang et al. in rodent fibroblasts and it was later …

Jan 9, 2025 · Latent Membrane Protein 1 (LMP-1) is a key player in the biology of Epstein-Barr Virus (EBV), significantly contributing to its pathogenesis. This viral protein is known for its role …

We have recently shown that LMP1 induces p62-mediated selective autophagy in EBV latency, at least by contributing to the induction of p62 expression, and Reactive Oxygen Species (ROS) …

Here, we review LMP1's molecular and biological functions, highlighting the interface between LMP1 and the cellular signal transduction network as an important factor of virus-host …

Sep 5, 2024 · Latent membrane protein 1 (LMP1) is the primary oncoprotein of Epstein-Barr virus (EBV) and plays versatile roles in the EBV life cycle and pathogenesis. Despite decades of …

Jun 28, 2018 · Oncogene LMP1 of Epstein–Barr virus (EBV) contributes to various tumors progress. In this study, we have provided strong evidence that LMP1 inhibits Sendai virus …

The Epstein-Barr virus oncoprotein LMP1 has six transmembrane domains (TMs) that enable intermolecular aggregation and constitutive signaling through two C-terminal cytosolic …

Dec 1, 2008 · LMP1 (MW 63 kDa) has a N-terminal hydrophilic domain (AA1–23) followed by six hydrophobic clusters forming three membrane spanning domains (TM1-3; AA24–186) and a …

LMP-1 has six membrane-spanning domains as opposed to CD40's one. LMP-1 also differs from CD40 in its apparent independence of a ligand for its signaling. We have examined the role of …