Establishment of an interleukin 2-dependent human T cell line from a patient with T cell chronic lymphocytic leukemia who is not infected with human T cell leukemia/lymphoma virus. The leukemia-lymphoma cell line factsbook.

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Kit225. A human T-cell line established from a patient with T-cell chronic lymphocytic leukemia. The cells express the markers CD3, CD4 but not CD8. The cells are not infected with HTLV I or II (Hori et al, 1987).

The table below shows data for the cell type and Nucleofector™ Platform selected. Those data are either based on Lonza Optimized Protocols or on results shared from customers who performed an optimization based on our guidelines.

May 29, 2024 · The current study investigates the differential contribution of IL-2 and IL-23 to the maintenance and differentiation of the IL-23 responsive Kit225 T-cell line. We observed that IL-23 enhanced cellular fitness and survival but was insufficient to drive proliferation.

We established an interleukin 2 (IL-2)-dependent human T cell line, Kit 225, from a patient with T cell chronic lymphocytic leukemia (T-CLL) with OKT3+, -T4+, -T8- phenotype.

Apr 15, 2016 · As an initial validation experiment, Kit225 cells known to respond to IL-12 stimulation 38 and expressing the IL-23R subunit were stimulated with recombinant human IL-23 and a time-dependent ...

Preassembly of interleukin 2 (IL-2) receptor subunits on resting Kit 225 K6 T cells and their modulation by IL-2, IL-7, and IL-15: a fluorescence resonance energy transfer study.

人淋巴T细胞系Kit225取自62岁男性T淋巴瘤白血病患者外周血，悬浮培养，形态偏圆，该细胞易发生聚团现象。 Characteristics: IL2 dependent. Omics: Transcriptome analysis. Derived from sampling site: Peripheral blood. Establishment of an interleukin 2-dependent human T cell line from a patient with T cell chronic lymphocytic leukemia who is not infected with human T cell leukemia/lymphoma virus.

Interleukin (IL)-23 mediated signal transduction represents a major molecular mechanism underlying the pathology of inflammatory bowel disease, Crohnâ €™ s disease and ulcerative colitis. In...