ISL1 is a marker for cardiac progenitors of the secondary heart field (SHF) which includes the right ventricle and the outflow tract. The biological function of ISL1 is demonstrated through …

Mar 30, 2025 · ISL1 (ISL LIM Homeobox 1) is a Protein Coding gene. Diseases associated with ISL1 include Bladder Exstrophy and Double Outlet Right Ventricle. Among its related …

Nov 25, 2021 · Isl1, a LIM-homeodomain transcription factor, acts as a key player in multiple organs during embryonic development. Its crucial roles in cardiovascular development have …

Overexpression of ISL1 in transplanted human mesenchymal stem promotes cell survival in a rat model of myocardial infarction and enhances their paracrine function to protect …

Nov 14, 2023 · ISL1 is a TF transiently expressed during emergence and expansion of multipotent progenitor second heart field (SHF) cells, before being downregulated upon further …

Apr 25, 2019 · Here we show that Isl1 acts as a pioneer factor driving cardiomyocyte lineage commitment by shaping the chromatin landscape of cardiac progenitor cells.

In this study, we generated Isl1 mutant mouse lines expressing graded doses of Isl1. Our study has revealed essential roles of Isl1 in multiple aspects of motor neuron development, including …

Feb 11, 2025 · Isl1 is an embryonic C-cell precursor marker that may be relevant also in cancer developed from the mature C-cell; A central role for Islet1 in the transition from sensory …

The LIM-homeodomain transcription factor Isl1 plays essential roles in cell proliferation, differentiation and survival during embryogenesis. To better visualize Isl1 expression and …

Isl1, a LIM-homeodomain transcription factor, acts as a key player in multiple organs during embryonic development. Its crucial roles in cardiovascular development have been elucidated …