A new lithocholic acid/IR 780 conjugate (LIC) was designed and synthesized for theranostic applications in triple-negative breast cancer. Lithocholic acid is an antitumor biomacromolecule and acts via multiple molecular targets. IR 780 iodide is a fluorescent NIR organic dye researched as a photothe …

IR 780 is a heptamethine cyanine fluorescent probe for in vivo imaging of tumor cells. 1 It displays excitation/emission maxima of 780/799 nm, respectively. 2 IR 780 is transported into tumor cells, an effect that can be blocked by the organic anion transporting polypeptide (OATP) inhibitor sulfobromophthalein (bromosulfalein; Item No. 21058 ...

IR780 is a prototypic NIR heptamethine cyanine agent, with a high molar extinction coefficient. The maximum excitation wavelength of IR780 was 777-780 nm, and the maximum emission wavelength was 798-823 nm. IR780 can be used in cancer PTT/PDT and imaging [1].

Phosphoric acid 2-hydroxyethyl methacrylate ester. Quick View. Sigma-Aldrich. 543349. IR-806. Quick View. Sigma-Aldrich. 795739. 11-Phosphonoundecyl acrylate. Quick View. Sigma-Aldrich. 543292. IR-783. ... IR-780 iodide is a near-infrared lipophilic cation heptamethine fluorescent dye. It has a good fluorescent intensity and can be used as a ...

Sep 1, 2013 · IR-780 is an important theranostic agent but its lipophilicity limited its application. In this paper, we synthesize multifunctional heparin–folic acid-IR-780 nanoparticles (HF-IR-780 NPs) by self-assembly of the heparin–folic acid conjugate and IR-780 through ultrasonic sound method.

Feb 5, 2021 · IR780 iodide, a promising near-infrared (NIR) dye, is receiving an increasing attention in the area of tumor imaging and is widely applied in photodynamic and photothermal therapy as it displays therapeutic potential to meet the dual goals of imaging and therapy as a theranostic agent [1].

IR-780 is an important theranostic agent but its lipophilicity limited its application. In this paper, we synthesize multifunctional heparin-folic acid-IR-780 nanoparticles (HF-IR-780 NPs) by self-assembly of the heparin-folic acid conjugate and IR-780 through ultrasonic sound method.

Feb 1, 2018 · In this study, we propose using IR 780-loaded, CD44-targeted hyaluronic acid-based micelles (HA-IR 780) for enhanced photothermal therapy (PTT) effects in tumors. Two kinds of HA-C18 micelles were synthesized from different C18 feed ratios with degree of substitution of 3% and 13% respectively.

IR-780 iodide, a near-infrared (near-IR) fluorescent dye, can be utilized as an effective theranostic agent for both imaging and photothermal therapy. However, its lipophilicity limits its further biomedical applications.

IR-780 is a near‐infrared fluorescent dye, is used for the exclusive characterization of human CSCs through the HIF‐1α/glycolysis dependent mitochondrial transporter ABCB10's activity. The maximum excitation wavelength of IR-780 was 777-780 nm, and the maximum emission wavelength was 798-823 nm.