Integra Dermal Regeneration Template (DRT) is the first and only FDA-approved skin substitute for the treatment of third degree burns and scar contracture proven to regenerate dermis. Integra's exclusive bilayer technology offers a novel bioengineered collagen and chondroitin-6-sulfate matrix combined with a protective silicone outer layer.

Jun 3, 2023 · It was initially used to safely cover large areas of burned tissue where skin needed to be regrown. However, Integra is now used far more widely as part of skin grafts in reconstructive surgery. Integra is sometimes referred to as a dermal matrix or dermal scaffold.

Integra Matrix Wound Dressing is indicated for the management of wounds including: partial and full-thickness wounds, pressure ulcers, venous ulcers, diabetic ulcers, chronic vascular ulcers, tunneled/undermined wounds, surgical wounds (donor sites/grafts, post-Moh’s surgery, post-laser surgery, podiatric, wound dehiscence), trauma wounds ...

Integra® Omnigraft Dermal Regeneration Matrix is indicated for use in the treatment of partial and full-thickness neuropathic diabetic foot ulcers that are greater than six weeks in duration, with no capsule, tendon or bone exposed, when used in conjunction with standard diabetic ulcer care.

First developed for coverage of burn wounds, Integra (Integra LifeSciences) is a synthetic acellular dermal regeneration template that provides a base for revascularization and neodermal formation. The use of Integra has slowly grown and has now ...

A benefit of INTEGRA® is that it does not require the use of a full-thickness autograft to cover the new dermis. This thin graft allows for a minimal donor site wound that heals faster. The...

It is designed to provide a solution for immediate coverage and closure of the wounds and functions jointly with a split-thickness skin graft (STSG) to regenerate a functional dermis . IDRT minimizes the risk of contracture and scar formation typically associated with skin grafting [ 5 ].

Integra® Bilayer Wound Matrix is an advanced bilayer matrix device consisting of a porous, three-dimensional dermal layer and a temporary epidermal layer. The dermal layer (collagen and glycosaminoglycan) provides a scaffold for cellular invasion and capillary growth.

In approximately 14 to 21 days, new dermal skin is produced and the silicone layer can be removed. A thin skin graft of the person's epidermis is applied to the wound area to complete the procedure.

Integra dermal regeneration templates are bilaminate regeneration templates composed of cross-linked bovine collagen and glycosaminoglycan, with an outer layer of silicone. 7,8 They are useful as a “scaffold” for neodermis formation, providing a viable skin graft recipient site over areas where primary skin grafting is not indicated. 9,10 ...