Nov 28, 2018 · In this study, we performed single-cell RNA sequencing (scRNA-seq) to determine the heterogeneity among IL-10-secreting CD4 T cells during persistent viral infection. …

Nov 10, 2021 · IL-10 is an anti-inflammatory cytokine that is known to modulate immune responses in GvHD. In this study, we evaluated the feasibility of transfecting IL-10 mRNA to …

Oct 25, 2021 · In this study, we have developed a nano-system to deliver inflammation-responsive Il-10 mRNA preferentially into macrophages for tailored inflammation control.

The chromatin structure of tightly regulated genes such as IL-10 are dynamically regulated by a process called “chromatin remodeling” to create accessibility to the gene by transcription …

Feb 8, 2025 · Title: Decreased Hepatic and Serum Levels of IL-10 Concur with Increased Lobular Inflammation in Morbidly Obese Patients. Genetic variants of IL-10 promoter influence …

Feb 15, 2010 · Interleukin-10 (IL-10), a cytokine with anti-inflammatory properties, has a central role in infection by limiting the immune response to pathogens and thereby preventing damage …

Nov 28, 2018 · To determine the transcriptional changes that underlie this adaption process, we applied a single-cell RNA-sequencing approach and assessed the heterogeneity of IL-10 …

We present an overview of the biological functions of IL-10, including some surprising new findings on nonclassical roles for this cytokine. We finish by summarizing the progress made …

IL-10 family cytokines exert essential functions to maintain tissue homeostasis during infection and inflammation through restriction of excessive inflammatory responses, upregulation of …

Interleukin-10 (IL-10), also known as ‘cytokine synthesis inhibitory factor’ (CSIF), is a pleiotropic cytokine with important immunoregulatory functions. It has anti-inflammatory properties and …