IRF7: role and regulation in immunity and autoimmunity - PMC
Interferon regulatory factor (IRF) 7 was originally identified as master transcriptional factor that produced IFN-I and regulated innate immune response, subsequent studies have revealed …
Interferon-α promotes MHC I antigen presentation of islet β cells ...
Our study demonstrated that STAT1-IRF7-MHC I complex axis were crucial for IFN-α signalling in islets, and created positive feedback through IRF7-STAT2 cascade amplifying signals which …
IRF7: activation, regulation, modification and function
Apr 14, 2011 · Interferon regulatory factor 7 (IRF7) was originally identified in the context of Epstein–Barr virus (EBV) infection, and has since emerged as the crucial regulator of type I...
Role of interferon regulatory factor 7 in corneal endothelial cells ...
Aug 13, 2021 · Interferon regulatory factor 7 (IRF7) has been identified as a significant regulator in corneal endothelial cells after an HSV-1 infection. To examine the role played by IRF7, the …
Uncovering the gene regulatory network of type 2 diabetes …
Dec 16, 2022 · IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory factor (IRF) family, which has been shown to play a role in the transcriptional activation of virus …
Interferon‐α promotes MHC I antigen presentation of islet β cells ...
Mar 17, 2022 · Our study demonstrated that STAT1-IRF7-MHC I complex axis were crucial for IFN-α signalling in islets, and created positive feedback through IRF7-STAT2 cascade …
The multiple roles of interferon regulatory factor family in health …
Oct 9, 2024 · Interferon regulatory factors (IRFs) constitute a comprehensive category of transcription factors initially identified as regulators of type I interferon (IFN-I) and IFN …
Interferon Regulatory Factor 7 Functions as a Novel Negative …
Our data demonstrate that IRF7 acts as a novel negative regulator of pathological cardiac hypertrophy by inhibiting nuclear factor-κB signaling and may constitute a potential therapeutic …
IRF7: role and regulation in immunity and autoimmunity
Aug 10, 2023 · Interferon regulatory factor (IRF) 7 was originally identified as master transcriptional factor that produced IFN-I and regulated innate immune response, subsequent …
Role of interferon regulatory factor 7 in corneal endothelial cells ...
Aug 13, 2021 · Interferon regulatory factor 7 (IRF7) has been identified as a significant regulator in corneal endothelial cells after an HSV-1 infection. To examine the role played by IRF7, the …
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