Interleukin-23 receptor - Wikipedia
It is encoded in human by the IL23R gene. [5] In complex with the interleukin-12 receptor β1 subunit , it is activated by the cytokine interleukin 23 (IL-23). [6] The IL23R mRNA is 2.8 …
Interleukin-23: as a drug target for autoimmune inflammatory …
A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science. 2006;314:1461–3. doi: 10.1126/science.1135245. [ DOI ] [ PMC free article ] [ …
IL23R Gene - GeneCards | IL23R Protein | IL23R Antibody
Dec 25, 2024 · IL23R (Interleukin 23 Receptor) is a Protein Coding gene. Diseases associated with IL23R include Inflammatory Bowel Disease 17 and Psoriasis 7 . Among its related …
IL23R gene - MedlinePlus
The IL23R gene provides instructions for making a protein called the interleukin 23 (IL-23) receptor. This protein is embedded in the outer membrane of several types of immune system …
Interleukin 23 receptor: Expression and ... - Wiley Online Library
Here, we focus on two questions: what are the immune cells that express the IL23R and how is IL23R expression acquired. The IL-23R: Structure and signaling IL-23 is a heterodimeric …
Interleukin-23 in the Pathogenesis of Inflammatory Bowel Disease …
IL-23 signalling via its cognate receptor promotes the survival and expansion of IL-17 and IL-22-producing Th17 cells, diminished by the presence of variants in IL23R conferring protection …
IL-23R is a senescence-linked circulating and tissue biomarker
Dec 10, 2024 · Il23r expression increased in the aged kidney, liver, perigonadal adipose and lung, which may reflect increased abundance of Il23r-expressing senescent cells and/or tissue …
The IL-23R and Its Genetic Variants: A Hitherto Unforeseen Bridge ...
Sivanesan D., Beauchamp C., Quinou C., Lee J., Lesage S., Chemtob S., Rioux J.D., Michnick S.W. IL23R (Interleukin 23 Receptor) Variants Protective against Inflammatory Bowel …
IL23R interleukin 23 receptor [ (human)] - National Center for ...
Feb 8, 2025 · IL23R gene is one of the genetic factors implicated in the genetics of IBD in the general population. We conclude that the IL23R gene does not seem to be associated with …
Characterisation of IL-23 receptor antagonists and disease
May 19, 2023 · We then develop a cyclic peptide fluorescent probe, specific to the IL23p19:IL23R interface and use this molecule to characterise further receptor antagonists.