IL-1RA is an agent that binds non-productively to the cell surface interleukin-1 receptor (IL-1R), the same receptor that binds interleukin 1 family (IL-1), preventing IL-1's from sending a signal …

Mar 30, 2025 · IL1RN (Interleukin 1 Receptor Antagonist) is a Protein Coding gene. Diseases associated with IL1RN include Chronic Recurrent Multifocal Osteomyelitis 2, With Periostitis …

highly significant ankylosing spondylitis association with markers in the IL1RN gene The genotype of interleukin-1 receptor antagonist seems to be associated with early-stage gastric cancer. …

Mar 2, 2021 · Interleukin-I receptor antagonist (IL1RN) is an immune modulatory molecule that commonly functions by means of competing the binding site of IL-1R with IL-1. Although it was …

Interleukin-1 receptor antagonist (IL1RN) is a potent anti-inflammatory molecule that modulates the biological activity of the proinflammatory cytokine, interleukin-1. The aim of this study was …

Feb 8, 2025 · Gene target information for IL1RN - interleukin 1 receptor antagonist (human). Find diseases associated with this biological target and compounds tested against it in bioassay …

Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and …

Jun 4, 2009 · Autoinflammatory diseases manifest inflammation without evidence of infection, high-titer autoantibodies, or autoreactive T cells. We report a disorder caused by mutations of …

Previous studies suggest that interleukin-1 receptor antagonist (IL-1ra) and single nucleotide polymorphisms (SNPs) in the IL1RN gene might influence the risk of post-stroke infection and …

IL1 receptor antagonist (IL1RN) is a protein that binds to IL1 receptors (IL1R1; 147810) and inhibits the binding of IL1-alpha (IL1A; 147760) and IL1-beta (IL1B; 147720). As a …