Interleukin-17A - Wikipedia
Interleukin-17A is a protein that in humans is encoded by the IL17A gene. In rodents, IL-17A used to be referred to as CTLA8, after the similarity with a viral gene (O40633). [5][6] The protein …
Interleukin 17 - Wikipedia
IL-17RA binds both IL-17A and IL-17F and is expressed in multiple tissues: vascular endothelial cells, peripheral T cells, B cell lineages, fibroblast, lung, myelomonocytic cells, and marrow …
Basic biology and role of interleukin-17 in immunity and inflammation
Interleukin-17 (IL-17, also known as IL-17A) is a key cytokine that links T cell activation to neutrophil mobilization and activation. As such, IL-17 can mediate protective innate immunity …
IL-17 Inhibitors: How They Work, What They Treat, Types
Mar 22, 2024 · IL-17 inhibitors block the inflammatory pathway of interleukin-17A. These biologic medications are an extremely effective FDA-approved treatment option for people with …
The IL-17 Family of Cytokines in Health and Disease - PubMed
Apr 16, 2019 · The interleukin 17 (IL-17) family of cytokines contains 6 structurally related cytokines, IL-17A through IL-17F. IL-17A, the prototypical member of this family, just passed …
The IL-17 family in diseases: from bench to bedside
Oct 11, 2023 · Interleukin 17 (IL-17) is an important cytokine that has several roles in host defense responses against mucosal infections; additionally, it is a primary pathologic cytokine …
IL-17A Inhibitor Use Associated With Increased IBD Risk - Medscape
17 hours ago · The anti–IL-17A group included 13,216 patients who initiated ixekizumab or secukinumab (mean age, 49.9 years; 54.9% women) who were propensity score matched to …
IL17A Gene - GeneCards | IL17 Protein | IL17 Antibody
Mar 30, 2025 · IL-17A plays a pivotal role in various infectious diseases, inflammatory and autoimmune disorders, and cancer. High levels of this cytokine are associated with several …
Interleukin-17A: The Key Cytokine in Neurodegenerative Diseases
Sep 28, 2020 · Interleukin-17A (IL-17A) is the signature cytokine of a subset of CD4 + helper T cells known as Th17 cells (McGeachy et al., 2019). The feature of Th17 cells is the expression …
IL17A interleukin 17A [Homo sapiens (human)] - Gene - NCBI
Feb 8, 2025 · IL-17A plays a pivotal role in various infectious diseases, inflammatory and autoimmune disorders, and cancer. High levels of this cytokine are associated with several …
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