Nov 3, 2020 · Knockdown of the cell adhesion protein CDH1 in encapsulated hPSC aggregates resulted in protrusion morphologies and emergence of extra-embryonic lineages, whereas …

Feb 26, 2025 · Cadherin 1 (CDH1)-mediated cell–cell contacts maintain the hPSC colony core, while the peripheral cells bind to extracellular fibers, primarily vitronectin, collagens, or …

Nov 1, 2020 · CDH1 in encapsulated hPSC aggregates resulted in protrusion morphologies and emergence of extra-embryonic lineages, whereas unencapsulated CDH1(-) aggregates …

May 12, 2020 · Here, we used plasma membrane profiling to directly measure cell-surface protein expression in naive and primed hPSC. This unbiased approach quantified over 1,700 plasma …

Hepatocyte nuclear factor 1B (HNF1B) encodes a transcription factor expressed in developing human kidney epithelia. Heterozygous HNF1B mutations are the commonest monogenic …

Nov 27, 2019 · Here, we combined genetic engineering with computational modeling, machine learning, and mathematical pattern optimization to create a data-driven approach to control …

Oct 1, 2024 · In this study, we introduced the human CDH1 and EGFP genes as a fusion protein into the AAVS1 locus using the CRISPR/Cas9 system in hFSiPS1 cells, a hiPSC line derived …

Jan 20, 2024 · CDH1, a PDX1 target in the rodent pancreas, has recently been confirmed to promote insulin (INS) secretion, resist apoptosis, glucotoxicity, lipotoxicity, and endoplasmic …

Nov 1, 2020 · Knockdown of the cell adhesion protein CDH1 in encapsulated hPSC aggregates resulted in protrusion morphologies and emergence of extra-embryonic lineages, whereas …

Oct 24, 2018 · We found that Cdh1 is highly expressed in human CD34 + HSPCs and downregulated in differentiated subsets; whereas, loss of Cdh1 restricts myeloid …