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Learn more about Bing search results hereOrganizing and summarizing search results for youHealthlinehttps://www.healthline.com › health › hypergammaglobulinemiaHypergammaglobulinemia: Causes, Symptoms, and Treatment - HealthlineHypergammaglobulinemia is an uncommon condition that is usually the result of an infection, autoimmune disorder, or malignancy such as multiple myeloma. It’s characterized by eleva…WebMDhttps://www.webmd.com › a-to-z-guides › immunoglobulin-testImmunoglobulin Test: High vs Low vs Normal Levels of (Ig) AntibodiesIf your immunoglobulin level is high, it might be caused by: Allergies Chronic infections An autoimmune disorder that makes your immune system overreact, such as rheumatoid arthrit…
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See all on WikipediaIgG4-related disease - Wikipedia
IgG4-related disease (IgG4-RD), formerly known as IgG4-related systemic disease, is a chronic inflammatory condition characterized by tissue infiltration with lymphocytes and IgG4-secreting plasma cells, various degrees of fibrosis (scarring) and a usually prompt response to oral steroids. In approximately 51–70% of … See more
IgG4-related disease has been described as an indolent condition. Although possibly based on opinion rather than on objective assessments, … See more
Whatever area of the body is involved, the hallmark histopathological features of IgG4-RD are:
1. A … See morePrior to 2011, IgG4-RD used to get mentioned in the medical literature under various different names. In addition, there are a number of … See more
Diagnosis requires tissue biopsy of an affected organ with characteristic histological findings, a comprehensive medical history and … See more
As recognition of IgG4-RD is relatively recent, there are limited studies on its epidemiology. It is therefore difficult to make an accurate … See more
• Overview of IgG4-related disease Archived 2020-09-23 at the Wayback Machine - UpToDate's article on IgG4-related disease.
• DermNet NZ entry See moreWikipedia text under CC-BY-SA license Treatment and prognosis of IgG4-related disease - UpToDate
Apr 8, 2025 · Common presentations include type 1 (IgG4-related) autoimmune pancreatitis (AIP); IgG4-related sclerosing cholangitis; major salivary gland enlargement or sclerosing …
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IgG4-related disease: why is it so important? - PMC
High levels of serum IgG4 were first detected in AIP1. The most common manifestation of this disease is obstructive jaundice (without any associated pain or fever) as a result of pancreatic …
Pathologies Associated with Serum IgG4 Elevation - PMC
IgG4-related disease (IgG4-RD) is usually associated to an increase of serum IgG4 levels. However other conditions have also been associated to high serum IgG4 levels. Methods. All IgG subclasses analyses performed in our hospital …
Diagnostic and treatment workup for IgG4-related disease - PMC
Great mimickers of IgG4-RD including pancreatic adenocarcinoma, lymphoma, and ANCA associated vasculitis can present with elevated serum IgG4 levels while biopsy confirmed …
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Clinical manifestations and diagnosis of IgG4-related disease
Mar 31, 2025 · Immunoglobulin G4-related disease (IgG4-RD) is an immune-mediated fibroinflammatory condition that is capable of affecting multiple organs . Organs affected by …
IgG4-Related Disease - Bone, Joint, and Muscle Disorders - Merck …
Immunoglobulin G4-related disease (IgG4-RD) is an uncommon immune disorder that usually affects multiple tissues and organs with tumor-like masses and/or painless enlargement. …
IgG4-Related Disease - StatPearls - NCBI Bookshelf
Aug 8, 2023 · IgG4 elevation more than two times the upper limit of normal (normal 140 mg/dL) has 99% specificity for IgG4-RD. Elevated IgG4 levels are nonspecific: five percent of persons …
IgG4-Related Disease - The Merck Manuals
Immunoglobulin G4-related disease (IgG4-RD) is a chronic immune-mediated fibroinflammatory disorder that often manifests with tumor-like masses and/or painless enlargement of multiple …
IgG4-related disease and other fibro-inflammatory conditions
Apr 7, 2025 · IgG4 responses have not been systematically investigated in ECD, but high IgG4 levels and prominent IgG4 + plasma-cell infiltration have been reported in case reports and …
