High-throughput screening (HTS) is a method for scientific discovery especially used in drug discovery and relevant to the fields of biology, materials science [1] and chemistry. [2][3] Using robotics, data processing/control software, liquid handling devices, and sensitive detectors, high-throughput screening allows a researcher to quickly ...

High-throughput screening (HTS) is an attractive methodology that may reduce the cost and attrition rate of drug development. This methodology exploits new technologies such as robotics, data processing/control software, liquid handling devices, and sensitive detectors to provide scientists with the means to rapidly screen enormous numbers of ...

High throughput screening (HTS) is the use of automated equipment to rapidly test thousands to millions of samples for biological activity at the model organism, cellular, pathway, or molecular level.

High-throughput screening (HTS) provides starting chemical matter in the adventure of developing a new drug. In this review, we survey several HTS methods used today for hit identification, organized in two main flavors: biochemical and cell-based assays.

HTP screening is a powerful tool in drug discovery, rapidly screening a large number of compounds to accelerate candidate identification and streamline drug development.

Jan 1, 2022 · HTS is a translational research technology used for identifying effectors (compounds, peptides, and biologics) that modulate target-specific biochemical or cell-based assays. In the context of small molecule drug discovery, HTS involves performing assays in the presence of large collections of compounds.

Apr 8, 2025 · High-throughput screening (HTS) is an essential technique in drug discovery used to quickly identify potential lead compounds from vast compound libraries. HTS enables researchers to test thousands or even millions of compounds in a short time frame to find those that interact with a specific biological target.

HTS is the process of screening large numbers of biological modulators against selected targets. HTS systems are used to screen different types of libraries such as chemical, genomics, protein, and peptide libraries.

Nov 18, 2024 · Despite its limitations, HTS has had a profound impact on drug discovery, accelerating the identification and development of novel therapeutics. By enabling the rapid screening of large compound libraries, HTS has significantly …

High-throughput screening (HTS) is a critical tool in modern drug discovery, enabling researchers to rapidly test large libraries of chemical or biological compounds against specific biological targets.